促红细胞生成素在休克和器官衰竭临床前模型中的有益作用。
Beneficial effects of erythropoietin in preclinical models of shock and organ failure.
作者信息
Thiemermann Christoph
机构信息
The William Harvey Research Institute, Queen Mary-University of London, Barts and The London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK.
出版信息
Crit Care. 2007;11(3):132. doi: 10.1186/cc5912.
Abstract
Erythropoietin protects many organs against the tissue injury and dysfunction caused by ischaemia/reperfusion and excessive inflammation. This editorial comment discusses the effects of erythropoietin in preclinical models of septic shock, endotoxemia, hemorrhagic shock, spinal cord trauma and zymosan-induced multiple organ failure.
摘要
促红细胞生成素可保护许多器官免受缺血/再灌注及过度炎症所导致的组织损伤和功能障碍。这篇社论评论探讨了促红细胞生成素在脓毒性休克、内毒素血症、失血性休克、脊髓损伤及酵母聚糖诱导的多器官功能衰竭的临床前模型中的作用。
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