[意大利儿童少关节起病的幼年型类风湿关节炎与HLA - A、B、DR]
[Juvenile rheumatoid arthritis with pauciarticular onset and HLA-A, B, DR in Italian children].
作者信息
Falcini F, Tafi L, Taccetti G, Trapani S, Menicucci A, Bartolozzi G
机构信息
Dipartimento di Pediatria, Clinica Pediatrica 1a, Università degli Studi di Firenze, Italia.
出版信息
Pediatr Med Chir. 1991 Jul-Aug;13(4):365-7.
Juvenile Rheumatoid Arthritis is a heterogeneous disease currently divided into different subtypes based on clinical characteristics. Significant alterations in frequencies of HLA-A, B and DR antigens have been described previously in children with pauciarticular onset Juvenile Rheumatoid Arthritis. We report the results of a study on 42 italian children with pauciarticular onset Juvenile Rheumatoid arthritis that partially confirm the literature data.
幼年类风湿性关节炎是一种异质性疾病，目前根据临床特征分为不同亚型。先前已有报道称，少关节型幼年类风湿性关节炎患儿的HLA-A、B和DR抗原频率有显著改变。我们报告了一项针对42名意大利少关节型幼年类风湿性关节炎患儿的研究结果，该结果部分证实了文献数据。
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