Shankar P R, Mishra P, Subish P, Upadhyay D K
Department of Pharmacology Manipal College of Medical Sciences, Pokhara, Nepal.
Pak J Pharm Sci. 2007 Jul;20(3):243-48.
Drug utilization research describes the extent, nature and determinants of drug use in populations and aims to facilitate the more rational use of medicines. The departments of Pharmacology and Clinical Pharmacy at the Manipal College of Medical Sciences, Pokhara, Nepal are committed to promoting the more rational use of medicines. The departments run a Drug Information Center and a Pharmacovigilance Center in the teaching hospital. Over the last eight years, the departments have conducted drug utilization studies in the teaching hospital and the community. A few of these were of the intervention type and drug use was studied before and after the intervention. Members of the departments are on the hospital Drug and Therapeutics Committee. Educational initiatives to improve prescribing have been carried out in a few instances. Restricting the number of brands in the hospital pharmacy and creation of a hospital drug list has been carried out. The impact of these initiatives has been studied only in a few cases. Generic prescribing was found to be low. The educational initiatives to improve prescribing had only limited success. The hospital is in the process of framing antimicrobial use guidelines for various departments. A hospital formulary is under preparation. The influence of drug utilization studies on the prescribing patterns has been low to moderate. The department of Clinical Pharmacy runs a Medication Counseling Center in the hospital and teaches appropriate use of medicines to patients. The studies and initiatives to promote the more rational use of medicines should be continued and strengthened.
药物利用研究描述了人群中药物使用的程度、性质和决定因素，旨在促进更合理地用药。尼泊尔博卡拉马尼帕尔医学科学学院的药理学和临床药学系致力于推动更合理地用药。这两个系在教学医院运营了一个药物信息中心和一个药物警戒中心。在过去八年里，这两个系在教学医院和社区开展了药物利用研究。其中一些是干预类型的研究，在干预前后对药物使用情况进行了研究。这两个系的成员是医院药物与治疗学委员会的成员。在一些情况下开展了旨在改善处方开具的教育举措。限制了医院药房品牌的数量，并制定了医院药品清单。这些举措的影响仅在少数案例中得到研究。发现通用名处方开具率较低。旨在改善处方开具的教育举措仅取得了有限的成功。医院正在为各个科室制定抗菌药物使用指南。一份医院处方集正在编写中。药物利用研究对处方模式的影响程度较低到中等。临床药学系在医院运营了一个用药咨询中心，并向患者传授合理用药知识。应继续并加强促进更合理用药的研究和举措。
