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在HIV预防试验中提供抗逆转录病毒治疗的义务。

The obligation to provide antiretroviral treatment in HIV prevention trials.

作者信息

Lo Bernard, Padian Nancy, Barnes Mark

机构信息

Program in Medical Ethics, Center for AIDS Prevention Studies and Division of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA.

出版信息

AIDS. 2007 Jun 19;21(10):1229-31. doi: 10.1097/QAD.0b013e3281338371.

DOI:10.1097/QAD.0b013e3281338371
PMID:17545698
Abstract

Providing antiretroviral therapy (ART) to participants who seroconvert during HIV prevention trials in developing countries is an ethical expectation. Promising treatment to the few seroconverters widens disparities within a resource-poor country and would be unjust. Such an assurance should be done in a way that also improves access to ART for others in the country. US funds for ART in poor countries from the PEPFAR should be available to all countries that host HIV prevention and clinical trials.

摘要

为在发展中国家进行的艾滋病预防试验中血清转化的参与者提供抗逆转录病毒疗法(ART)是一项道德期望。向少数血清转化者承诺提供治疗会加剧资源匮乏国家内部的差距,而且是不公正的。这种保障措施应以同时改善该国其他人群获得抗逆转录病毒疗法的方式来实施。美国通过总统防治艾滋病紧急救援计划(PEPFAR)为贫穷国家提供的抗逆转录病毒疗法资金应提供给所有开展艾滋病预防和临床试验的国家。

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引用本文的文献

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AJOB Prim Res. 2012;3(4):30-39. doi: 10.1080/21507716.2012.714836.
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Post-trial access to antiretrovirals: who owes what to whom?抗逆转录病毒药物的试用后获取:谁欠谁的?
Bioethics. 2011 Mar;25(3):145-54. doi: 10.1111/j.1467-8519.2009.01736.x.
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Subjects' views of obligations to ensure post-trial access to drugs, care and information: qualitative results from the Experiences of Participants in Clinical Trials (EPIC) study.
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J Med Ethics. 2009 Mar;35(3):183-8. doi: 10.1136/jme.2008.024711.
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World AIDS Day 2007: AIDS at 26, are we there yet?2007年世界艾滋病日:艾滋病流行26年了,我们成功了吗?
Retrovirology. 2007 Dec 1;4:86. doi: 10.1186/1742-4690-4-86.