Kline Mark W
The Baylor International Pediatric AIDS Initiative, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.
Pediatrics. 2006 Apr;117(4):1388-93. doi: 10.1542/peds.2005-1348.
The successes of the United States and other developed countries in the prevention and treatment of pediatric HIV/AIDS have not been replicated in the developing world, where children continue to become infected with HIV and die from HIV/AIDS at astounding rates. Children are underrepresented among recipients of antiretroviral therapy in almost every setting worldwide where treatment programs have been established. The barriers to scaling up HIV/AIDS care and treatment globally are substantial. Nevertheless, nearly a decade after the introduction of pediatric highly active antiretroviral therapy in the United States, the opportunity finally exists to provide treatment to huge numbers of HIV-infected children in the developing world, changing forever the way that pediatric HIV/AIDS is perceived and managed. We propose the creation of a Clinical Centers of Excellence Network and Pediatric AIDS Corps of US pediatric health professionals, increased support for pediatric research relevant to resource-poor settings, commitment of the US government and others to proportionate funding for pediatric HIV/AIDS care and treatment, expanded availability of pediatric antiretroviral drug formulations, and a renewed commitment to collaborative partnerships as practical steps that can be taken to dramatically expand access of HIV-infected children and families in the developing world to health-restoring, life-prolonging care and treatment.
美国和其他发达国家在预防和治疗儿童艾滋病毒/艾滋病方面所取得的成功，在发展中世界并未得到重现。在发展中世界，儿童感染艾滋病毒的情况仍在继续，并且正以惊人的速度死于艾滋病毒/艾滋病。在全球几乎每一个已设立治疗项目的地方，接受抗逆转录病毒疗法的儿童人数都偏低。在全球范围内扩大艾滋病毒/艾滋病护理和治疗存在巨大障碍。然而，在美国引入儿童高效抗逆转录病毒疗法近十年后，终于有机会为发展中世界大量感染艾滋病毒的儿童提供治疗，这将永远改变人们对儿童艾滋病毒/艾滋病的认知和管理方式。我们提议创建一个由美国儿科健康专业人员组成的卓越临床中心网络和儿科艾滋病防治队，增加对与资源匮乏地区相关的儿科研究的支持，美国政府及其他方面承诺按比例为儿童艾滋病毒/艾滋病护理和治疗提供资金，扩大儿科抗逆转录病毒药物配方的供应，并重新致力于建立合作伙伴关系，作为可以采取的切实步骤，以大幅扩大发展中世界感染艾滋病毒的儿童及其家庭获得恢复健康、延长生命的护理和治疗的机会。
