Kunik Mark E, Walgama Jonathan P, Snow A Lynn, Davila Jessica A, Schulz Paul E, Steele Avila B, Morgan Robert O
Houston Center for Quality of Care and Utilization Studies, Michael E. DeBakey Veterans Affairs Medical Center, and Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, TX 77030, USA.
Alzheimer Dis Assoc Disord. 2007 Apr-Jun;21(2):115-21. doi: 10.1097/WAD.0b013e318065c4ba.
Practice guidelines recommend a search for underlying biopsychosocial causes and initial use of nonpharmacologic interventions. Using guidelines as a benchmark for standard care, we examined medical records to assess the documentation, assessment, and treatment of aggression in patients newly diagnosed with dementia. Study participants were at least 60 years old and diagnosed with dementia at the Michael E. DeBakey VA Medical Center in Houston, TX, from 2001 to 2004. Of 385 eligible patients screened by telephone using 3 probes from the Ryden Aggression Scale, 75 had positive response to 1 or more of 3 probes from the Ryden. Medical records of these patients were reviewed for 12 months before and 3 months after telephone screening. Aggression had been documented in 31 (42%), nonpharmacologic interventions had been used in 11 (35%), and pharmacologic interventions had been used in all 31. Among the 44 patients without previously documented aggression, pharmacologic interventions were used in 34 (79%) patients. Patients with documented aggression had more psychiatric comorbidities and received more psychotropic medications than patients with undocumented aggression. We conclude that dementia patients should be systematically screened for aggression and that new strategies to increase use of nonpharmacologic interventions and decrease use of pharmacologic interventions, particularly antipsychotics, should be identified.
实践指南建议寻找潜在的生物心理社会原因,并首先使用非药物干预措施。我们以指南作为标准护理的基准,检查了病历,以评估新诊断为痴呆症患者攻击行为的记录、评估和治疗情况。研究参与者年龄至少60岁,于2001年至2004年在德克萨斯州休斯顿的迈克尔·E·德贝基退伍军人事务医疗中心被诊断为痴呆症。在通过电话使用赖登攻击量表的3个问题对385名符合条件的患者进行筛查时,75名患者对赖登量表的3个问题中的1个或更多问题有阳性反应。对这些患者在电话筛查前12个月和筛查后3个月的病历进行了审查。有31名(42%)患者记录了攻击行为,11名(35%)患者使用了非药物干预措施,所有31名患者都使用了药物干预措施。在44名之前未记录攻击行为的患者中,34名(79%)患者使用了药物干预措施。与未记录攻击行为的患者相比,记录了攻击行为的患者有更多的精神科合并症,并且接受了更多的精神药物治疗。我们得出结论,应该对痴呆症患者进行系统的攻击行为筛查,并且应该确定新的策略,以增加非药物干预措施的使用并减少药物干预措施的使用,特别是抗精神病药物的使用。