预激综合征患者同时使用锂盐和普罗帕酮引起的Brugada型心电图改变

Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome.

作者信息

Fragakis Nikolaos, Iliadis Ilias, Papanastasiou Soultana, Lambrou Alexandra, Katsaris George

机构信息

Second Cardiac Department, GH G. Papanikolaou, Thessaloniki, Greece.

出版信息

Pacing Clin Electrophysiol. 2007 Jun;30(6):823-5. doi: 10.1111/j.1540-8159.2007.00762.x.

DOI:10.1111/j.1540-8159.2007.00762.x

PMID:17547624

Abstract

We report a case of ST elevation in right precordial leads compatible with type 1 Brugada syndrome following administration of propafenone in a patient with Wolff-Parkinson-White syndrome who was receiving lithium at concentrations within therapeutic levels. The mechanism of the electrocardiogram changes was considered to be caused by the two drugs synergistic sodium channel blocking effects.

摘要

我们报告一例患有 Wolff-Parkinson-White 综合征且锂浓度处于治疗水平的患者，在服用普罗帕酮后出现右胸前导联 ST 段抬高，符合 1 型 Brugada 综合征。心电图变化的机制被认为是由这两种药物协同的钠通道阻滞作用引起的。