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水疱性疾病有哪些新进展?

What's new in blistering disorders?

作者信息

Chaudhari Paru, Marinkovich M Peter

机构信息

Stanford University School of Medicine and VA Palo Alto Medical Center, 269 Campus Drive, Room 2145, Stanford, CA 94061, USA.

出版信息

Curr Allergy Asthma Rep. 2007 Jul;7(4):255-63. doi: 10.1007/s11882-007-0038-7.

Abstract

From the characterization of new animal models for the study of disease pathogenesis, to the demonstration of new therapeutic modalities, many developments have revolutionized the field of autoimmune bullous diseases in the past several years. This review highlights many of the significant advances that have taken place in the diagnosis, pathogenesis, and treatment options for pemphigus, pemphigoid, epidermolysis bullosa acquisita, and immunoglobulin (Ig) A-mediated bullous disorders.

摘要

从用于疾病发病机制研究的新动物模型的特征描述,到新治疗方式的展示,在过去几年里,许多进展彻底改变了自身免疫性大疱性疾病领域。本综述重点介绍了天疱疮、类天疱疮、获得性大疱性表皮松解症和免疫球蛋白(Ig)A介导的大疱性疾病在诊断、发病机制和治疗选择方面取得的许多重大进展。

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