Tous Horacio M, Nevárez Juan
Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus.
P R Health Sci J. 2006 Dec;25(4):319-23.
To analyze and compare the main outcomes between trabeculectomies combined with extracapsular cataract extraction (ECCE) versus those with phacoemulsification (Phaco).
The authors retrospectively reviewed one surgeon's 357 consecutive cases (475 eyes) of combined cataract extraction, intraocular lens implantation and Mitomycin enhanced trabeculectomy. Patients were divided into two groups, those who underwent extracapsular cataract extraction (80 eyes) and those having phacoemulsification (395 eyes). Analysis of postoperative visual acuity, intraocular pressure (IOP), number of glaucoma medications, postoperative adverse events and additional procedures required, was done. Minimum follow-up was 12 months with an average of 53 months.
There was no significant difference (p = 1.000) between the groups in terms of visual acuity improvement rate, 66% (ECCE) versus 59% (Phaco). Postoperatively IOP with both techniques fell significantly (p < 0.0001). Earlier IOP reduction was obtained with Phacoemulsification, but there was no difference by the end of the follow up period (14.4 mmHg ECCE vs. 14.1 mmHg Phaco, p = 1.0000). Postoperative pressure spikes occurred in 6% versus 10% (p = 0.3995) of the eyes. No significant difference (55% ECCE versus 63% Phaco, p = 0.1674) between the two groups in terms of glaucoma medication reduction was found. The total number of postoperative complications (89% versus 68.5%) were significantly higher (p = 0.0001) in the ECCE-group, as well as the total number of eyes which required further interventions (86% versus 64%, p = 0.0001).
Both combined surgery techniques are effective and yielded similar long-term results. However phacoemulsification can decrease the post operative complications associated with this surgery.
分析并比较小梁切除术联合白内障囊外摘除术(ECCE)与小梁切除术联合超声乳化白内障吸除术(Phaco)的主要手术效果。
作者回顾性分析了一位外科医生连续进行的357例(475只眼)白内障摘除、人工晶状体植入联合丝裂霉素强化小梁切除术的病例。患者被分为两组,即接受白内障囊外摘除术的患者(80只眼)和接受超声乳化白内障吸除术的患者(395只眼)。对术后视力、眼压(IOP)、青光眼用药数量、术后不良事件以及所需的额外手术进行了分析。最短随访时间为12个月,平均随访时间为53个月。
两组在视力改善率方面无显著差异(p = 1.000),白内障囊外摘除术组为66%,超声乳化白内障吸除术组为59%。两种手术方式术后眼压均显著下降(p < 0.0001)。超声乳化白内障吸除术眼压降低更早,但随访期末无差异(白内障囊外摘除术组14.4 mmHg,超声乳化白内障吸除术组14.1 mmHg,p = 1.0000)。术后眼压峰值在白内障囊外摘除术组和超声乳化白内障吸除术组分别为6%和10%(p = 0.3995)。两组在减少青光眼用药方面无显著差异(白内障囊外摘除术组55%,超声乳化白内障吸除术组63%,p = 0.1674)。白内障囊外摘除术组术后并发症总数(89%对68.5%)以及需要进一步干预的眼数(86%对64%)均显著更高(p = 0.0001)。
两种联合手术技术均有效且长期效果相似。然而,超声乳化白内障吸除术可减少该手术相关的术后并发症。