Tous Horacio M, Nevárez Juan
Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus.
P R Health Sci J. 2007 Mar;26(1):29-33.
To analyze and compare the main outcomes of two techniques of combined surgery; mitomycin enhanced trabeculectomy combined with phacoemulsification and intraocular lens implantation through a single incision versus a two incisions approach.
The authors retrospectively reviewed one surgeon's consecutive 395 combined phacoemulsification/trabeculectomy surgeries. Patients were divided into two groups, those who underwent phacoemulsification and intraocular lens implantation through one incision (Phaco 1) and the other through two incisions (Phaco 2), both combined with trabeculectomy. Analysis of postoperative visual acuity, intraocular pressure, number of glaucoma medications, postoperative adverse events and additional procedures required, was done. Minimum follow-up was 12 months with an average of 49.2 months.
There was a significant difference (p = 0.0237) between the groups in terms of visual acuity improvement rate. By the end of the follow up period, both techniques were equally effective in reducing IOPs by an average of 8.1 mmHg. Postoperative pressure spikes occurred in 9% versus 11% (p = 0.6838) of the eyes. No significant difference (63% Phaco 1 versus 69% Phaco 2, p = 0.3230) between the two groups in terms of glaucoma medication reduction was found. There was no significant difference (p = 0.1181), in the total postoperative complications between the two groups (60% Phaco 1 vs. 51% Phaco 2), as well as in the total number of eyes which required further interventions (60% versus 68%, p = 0.2223).
Combined phacoemulsification/ trabeculectomy using either a single or a two site approach, are equally effective in treating glaucoma patients with cataracts.
分析并比较两种联合手术技术的主要结果;丝裂霉素强化小梁切除术联合白内障超声乳化吸除及人工晶状体植入术,采用单切口与双切口两种入路方式。
作者回顾性分析了一位外科医生连续进行的395例白内障超声乳化吸除术/小梁切除术联合手术。患者被分为两组,一组通过单切口进行白内障超声乳化吸除及人工晶状体植入术(超声乳化单切口组),另一组通过双切口进行(超声乳化双切口组),两组均联合小梁切除术。对术后视力、眼压、青光眼用药数量、术后不良事件及所需额外手术进行分析。最短随访时间为12个月,平均随访时间为49.2个月。
两组在视力改善率方面存在显著差异(p = 0.0237)。随访期末,两种技术在平均降低眼压8.1 mmHg方面同样有效。术后眼压峰值在两组眼中的发生率分别为9%和11%(p = 0.6838)。两组在减少青光眼用药方面无显著差异(超声乳化单切口组为63%,超声乳化双切口组为69%,p = 0.3230)。两组在术后总并发症方面(超声乳化单切口组为60%,超声乳化双切口组为51%)以及需要进一步干预的眼数方面(60%对68%,p = 0.22)均无显著差异(p = 0.1181)。
采用单切口或双切口入路的白内障超声乳化吸除术/小梁切除术联合手术,在治疗合并白内障的青光眼患者时同样有效。