成人干细胞或祖细胞用于1型糖尿病治疗：当前进展
Adult stem or progenitor cells in treatment for type 1 diabetes: current progress.
作者信息
Liao Yu Huan T, Verchere C Bruce, Warnock Garth L
机构信息
Ike Barber Human Islet Transplant Laboratory, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
出版信息
Can J Surg. 2007 Apr;50(2):137-42.
Abstract
Since the development of the Edmonton Islet Transplantation Protocol, islet transplantation has given new hope to patients with type 1 diabetes. Like solid organ transplantation, one of the biggest challenges islet transplantation faces is the shortage of available donor tissue. Finding an alternative source of islet tissue has become an increasingly important field of study. The possibility of generating insulin-secreting cells and islet tissue with adult pancreatic stem or progenitor cells has been investigated extensively. This review aims to discuss recent progress in the study of adult pancreatic stem or progenitor cells and to suggest future directions in this field.
摘要
自从埃德蒙顿胰岛移植方案制定以来，胰岛移植给1型糖尿病患者带来了新希望。与实体器官移植一样，胰岛移植面临的最大挑战之一是可用供体组织短缺。寻找胰岛组织的替代来源已成为一个日益重要的研究领域。利用成人胰腺干细胞或祖细胞生成胰岛素分泌细胞和胰岛组织的可能性已得到广泛研究。本综述旨在讨论成人胰腺干细胞或祖细胞研究的最新进展，并提出该领域未来的发展方向。
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本文引用的文献
1
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?长期1型糖尿病患者中持续的β细胞凋亡：胰岛再生的间接证据？
Diabetologia. 2005 Nov;48(11):2221-8. doi: 10.1007/s00125-005-1949-2. Epub 2005 Oct 5.
2
Regeneration of the pancreatic beta cell.胰腺β细胞的再生
J Clin Invest. 2005 Jan;115(1):5-12. doi: 10.1172/JCI23935.
3
The pancreatic ductal epithelium serves as a potential pool of progenitor cells.胰腺导管上皮作为祖细胞的潜在来源。
Pediatr Diabetes. 2004;5 Suppl 2:16-22. doi: 10.1111/j.1399-543X.2004.00075.x.
4
Insulin therapy and hypoglycaemia: the size of the problem.胰岛素治疗与低血糖：问题的严重程度
Diabetes Metab Res Rev. 2004 Nov-Dec;20 Suppl 2:S32-42. doi: 10.1002/dmrr.514.
5
Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.β细胞复制是维持出生后β细胞数量的主要机制。
J Clin Invest. 2004 Oct;114(7):963-8. doi: 10.1172/JCI22098.
6
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages.从成年小鼠胰腺中克隆鉴定出可产生神经和胰腺谱系的多能前体细胞。
Nat Biotechnol. 2004 Sep;22(9):1115-24. doi: 10.1038/nbt1004. Epub 2004 Aug 22.
7
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Diabetes. 2004 Aug;53(8):2143-52. doi: 10.2337/diabetes.53.8.2143.
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J Endocrinol. 2004 Jul;182(1):105-12. doi: 10.1677/joe.0.1820105.
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