系统生物学：性别转换开关。

Systems biology: a switch for sex.

作者信息

Andrews Steven S, Arkin Adam P

机构信息

Physical Biosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, M.S. 977-152, Berkeley, California 94720, USA.

出版信息

Curr Biol. 2007 Jun 5;17(11):R410-2. doi: 10.1016/j.cub.2007.03.060.

DOI:10.1016/j.cub.2007.03.060

PMID:17550765

Abstract

The yeast pheromone response pathway works in a graded fashion, such that more pheromone leads to more response, but a recent study has shown that small modifications convert it into a bistable switch, with implications for the evolution and engineering of reaction networks.

摘要

酵母信息素反应途径以分级方式起作用，即更多的信息素会导致更多的反应，但最近的一项研究表明，微小的修饰可将其转化为双稳态开关，这对反应网络的进化和工程设计具有重要意义。