快速致死性棘阿米巴脑炎与冷球蛋白血症的治疗
Rapidly fatal Acanthamoeba encephalitis and treatment of cryoglobulinemia.
作者信息
Meersseman Wouter, Lagrou Katrien, Sciot Raf, de Jonckheere Johan, Haberler Christine, Walochnik Julia, Peetermans Willy E, van Wijngaerden Eric
机构信息
Division of General Internal Medicine, Gasthuisberg University Hospital, Leuven, Belgium.
出版信息
Emerg Infect Dis. 2007 Mar;13(3):469-71. doi: 10.3201/eid1303.061001.
Abstract
We describe a 66-year-old woman with therapy-refractory cryoglobulinemia treated with rituximab, plasmapheresis, and steroids; a case of fatal meningoencephalitis caused by Acanthamoeba spp. then developed. Such infections are rare and show an unusually rapid course (possibly related to rituximab).
摘要
我们描述了一名66岁患有难治性冷球蛋白血症的女性，接受了利妥昔单抗、血浆置换和类固醇治疗；随后发生了一例由棘阿米巴属引起的致命性脑膜脑炎。此类感染罕见且病程异常迅速（可能与利妥昔单抗有关）。
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