Benhamou A H, Eigenmann P A
Département de pédiatrie, HUG, 1211 Genève 14.
Rev Med Suisse. 2007 Apr 25;3(108):1038-43.
Around 13% of children in Switzerland are affected by atopic dermatitis. Cutaneous defects with increased water loss and allergens permeability are hallmark of the disease. The prevalence of food allergy in children with moderate-to-severe atopic dermatitis is estimated to be 34%, mostly to eggs, milk and peanuts. Food allergy can cause immediate reactions with urticaria and anaphylaxis or delayed flares of eczema. In older patients and adults, exposition to respiratory allergens (dust mites, pollen) can also cause an exacerbation of the eczema. Allergy testing identifies patients with atopy, who are at greater risk of rhinitis and asthma. Skin prick tests, in vitro tests and food challenges can identify a concomitant allergy, leading to specific allergen avoidance mea-sures potentially improving skin symptoms.
瑞士约13%的儿童患有特应性皮炎。皮肤水分流失增加和过敏原通透性增加的皮肤缺陷是该疾病的标志。中重度特应性皮炎患儿的食物过敏患病率估计为34%,主要是对鸡蛋、牛奶和花生过敏。食物过敏可引起荨麻疹和过敏反应等即刻反应,或湿疹的延迟发作。在年龄较大的患者和成年人中,接触呼吸道过敏原(尘螨、花粉)也可导致湿疹加重。过敏测试可识别出患有特应性疾病的患者,他们患鼻炎和哮喘的风险更高。皮肤点刺试验、体外试验和食物激发试验可识别出合并存在的过敏,从而采取特定的避免接触过敏原措施,这可能改善皮肤症状。