Hofer M F
Service de pédiatrie, CHUV, Lausanne.
Rev Med Suisse Romande. 2000 Mar;120(3):263-7.
Atopic dermatitis is an early manifestation of atopy and is frequently present already during the first year of life. Atopic dermatitis is often associated with increased levels of serum IgE and with sensitization to food allergens. Some foods may be responsible for exacerbations of skin inflammation, but their pathogenic role need to be clinically assessed before an avoidance diet is prescribed. Staphylococcus aureus, which is known to colonize the skin of atopic dermatitis patients, may also exacerbate skin lesions and need to be treated with topical antibiotics. Children with atopic dermatitis are prone to allergies and are at risk to develop later respiratory allergic manifestations. In particular, if a sensitization to egg is present early in life, the risk for developing later an asthma due to house dust mites is increased. The care of children with atopic dermatitis should not be limited to the treatment of skin lesions, but should also involve preventive measures for respiratory allergies.
特应性皮炎是特应性的早期表现,常在生命的第一年就已出现。特应性皮炎常与血清IgE水平升高以及对食物过敏原致敏有关。某些食物可能导致皮肤炎症加重,但在规定避免食用某些食物的饮食之前,其致病作用需要进行临床评估。已知金黄色葡萄球菌可定植于特应性皮炎患者的皮肤,它也可能加重皮肤损害,需要用外用抗生素治疗。患有特应性皮炎的儿童容易过敏,日后有发生呼吸道过敏表现的风险。特别是,如果在生命早期就对鸡蛋致敏,日后因屋尘螨而患哮喘的风险会增加。对患有特应性皮炎儿童的护理不应仅限于皮肤损害的治疗,还应包括呼吸道过敏的预防措施。