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希腊医护人员中HIV暴露情况及暴露后预防的监测

Surveillance of HIV exposure and postexposure prophylaxis among health care workers in Greece.

作者信息

Konte Vasileia, Nikolopoulos Georgios, Raftopoulos Vasilios, Pylli Magda, Tsiara Chrissa, Makri Efraxia, Paraskeva Dimitra

机构信息

HIV Office, Hellenic Centre for Diseases Control and Prevention, Athens, Greece.

出版信息

Public Health Nurs. 2007 Jul-Aug;24(4):337-42. doi: 10.1111/j.1525-1446.2007.00642.x.

Abstract

OBJECTIVE

Many developed countries have implemented surveillance systems for monitoring occupational exposure to HIV. The aim of the present study was to analyze surveillance data on HIV postexposure prophylaxis (PEP) for health care workers (HCWs) in Greece.

DESIGN

All data reported to the Hellenic Centre for Disease Control and Prevention between January 1996 and June 2005 were analyzed. SAMPLE AND MEASUREMENT: 188 reported occupational exposures to HIV were analyzed, retrospectively.

RESULTS

Most exposures were in the physicians (37.8%), followed by the nursing personnel (18.6%). Nearly 38% of the HCWs were males and the predominant type of biological material involved in the exposure was blood (74.5%). Two drugs were used for PEP in 23.4% of the HCWs, and 3 drugs in 66.5% of the reported cases.

CONCLUSIONS

Greek guidelines provide guidance for treating HCWs after occupational exposure to HIV. In our study, antiretroviral treatment, a three-drug regimen in the majority of the cases, was prescribed after evaluation of specially appointed physicians. The surveillance system of occupational exposure to HIV in HCWs should be further developed and enhanced in order to monitor and evaluate the risk factors surrounding the incidents.

摘要

目的

许多发达国家已实施监测系统,以监测医护人员的职业性HIV暴露情况。本研究旨在分析希腊医护人员HIV暴露后预防(PEP)的监测数据。

设计

对1996年1月至2005年6月期间报告给希腊疾病控制与预防中心的所有数据进行分析。

样本与测量

回顾性分析188例报告的职业性HIV暴露情况。

结果

大多数暴露发生在医生身上(37.8%),其次是护理人员(18.6%)。近38%的医护人员为男性,暴露所涉及的主要生物材料类型为血液(74.5%)。23.4%的医护人员使用两种药物进行PEP,66.5%的报告病例使用三种药物。

结论

希腊指南为医护人员职业性HIV暴露后的治疗提供了指导。在我们的研究中,经过指定医生评估后,大多数病例采用了三种药物的抗逆转录病毒治疗方案。应进一步发展和加强医护人员职业性HIV暴露监测系统,以监测和评估事件周围的风险因素。

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