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HIV暴露后预防:哪些人应该接受?

HIV postexposure prophylaxis: Who should get it?

作者信息

Campos-Outcalt Doug

机构信息

Department of Family and Community Medicine, University of Arizona College of Medicine, 4001 North Third Street #415, Phoenix, AZ 85012, USA.

出版信息

J Fam Pract. 2006 Jul;55(7):600-4.

PMID:16822447
Abstract

In most cases, HIV postexposure prophylaxis (PEP) is given only to healthcare workers if the settings make exposure to HIV-infected persons likely. Otherwise, it is usually deemed unnecessary. However, a decision for or against PEP is complicated. Occupational and nonoccupational exposure to HIV can produce fear, anxiety, and stress. Information on the exposure risk is frequently incomplete, the risk of infection is usually low, the degree of protection offered by PEP is not fully defined, and the potential for side effects from the medications is significant. This article distills the Centers for Disease Control and Prevention's most recent guidance on HIV PEP.

摘要

在大多数情况下,只有当工作环境可能导致医护人员接触到感染艾滋病毒的人员时,才会对其进行艾滋病毒暴露后预防(PEP)。否则,通常认为没有必要。然而,决定是否进行PEP很复杂。职业性和非职业性接触艾滋病毒会产生恐惧、焦虑和压力。关于暴露风险的信息往往不完整,感染风险通常较低,PEP提供的保护程度尚未完全明确,而且药物的潜在副作用很大。本文提炼了美国疾病控制与预防中心关于艾滋病毒PEP的最新指南。

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