Islam Najmul, Shahpurwala Munira Mehboob, Siddiqui Bilal Karim, Khan Javaid A
Department of Medicine, The Aga Khan University, Karachi, Pakistan.
J Coll Physicians Surg Pak. 2007 May;17(5):283-5.
Papillary carcinoma of thyroid tends to be indolent. This is an unusual case of papillary carcinoma of thyroid with asymptomatic pulmonary metastasis for more than a decade, finally presenting with mild respiratory symptoms in a 21-year-old female. Fine needle aspiration and cytology (FNA-C) of a nodule in the lungs revealed features consistent with a papillary carcinoma of thyroid. Confirmed on thyroidectomy specimen. She subsequently received Iodine-131 (I131). A follow-up radio-iodide scan, 48 hours after, revealed diffuse uptake within the lung parenchyma. With static nodular shadowing on radiograph, a metastatic origin, in particular that of the thyroid, should be considered. I131 scintigraphy can help support the diagnosis of carcinoma of thyroid.
甲状腺乳头状癌往往生长缓慢。这是一例不寻常的甲状腺乳头状癌病例,一名21岁女性出现无症状肺转移超过十年,最终出现轻微呼吸道症状。对肺部结节进行细针穿刺抽吸及细胞学检查(FNA-C)显示其特征与甲状腺乳头状癌相符。甲状腺切除标本确诊。她随后接受了碘-131(I131)治疗。48小时后的后续放射性碘扫描显示肺实质内弥漫性摄取。鉴于胸部X线片上有静态结节阴影,应考虑转移瘤的起源,尤其是甲状腺来源。I131闪烁扫描有助于支持甲状腺癌的诊断。