脂联素与肾脏疾病进展：另一个流行病学难题？
Adiponectin and renal disease progression: another epidemiologic conundrum?
作者信息
Zoccali C, Mallamaci F
机构信息
Dialisi e Trapianto Renale Ospedali Riuniti, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell'Ipertensione Arteriosa, Reggio Calabria, Italy.
出版信息
Kidney Int. 2007 Jun;71(12):1195-7. doi: 10.1038/sj.ki.5002319.
PMID:17554349
Abstract
In an analysis based on the Mild to Moderate Kidney Disease (MMKD) study, adiponectin, a pleiotropic, insulin-sensitizing, anti-inflammatory and vasculo-protective cytokine, was directly related to renal disease progression. The precise definition of this apparently paradoxical association now requires that the research focus be moved from the study database to the experimental laboratory.
摘要
在一项基于轻度至中度肾病（MMKD）研究的分析中，脂联素是一种具有多效性、胰岛素增敏、抗炎和血管保护作用的细胞因子，它与肾脏疾病进展直接相关。对于这种明显矛盾的关联的确切定义，现在需要将研究重点从研究数据库转移到实验实验室。
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