• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Segmental uniparental disomy as a recurrent mechanism for homozygous CEBPA mutations in acute myeloid leukemia.

作者信息

Wouters B J, Sanders M A, Lugthart S, Geertsma-Kleinekoort W M C, van Drunen E, Beverloo H B, Löwenberg B, Valk P J M, Delwel R

出版信息

Leukemia. 2007 Nov;21(11):2382-4. doi: 10.1038/sj.leu.2404795. Epub 2007 Jun 7.

DOI:10.1038/sj.leu.2404795
PMID:17554374
Abstract
摘要

相似文献

1
Segmental uniparental disomy as a recurrent mechanism for homozygous CEBPA mutations in acute myeloid leukemia.节段性单亲二体作为急性髓系白血病中纯合性CEBPA突变的反复出现机制。
Leukemia. 2007 Nov;21(11):2382-4. doi: 10.1038/sj.leu.2404795. Epub 2007 Jun 7.
2
Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias.急性髓系白血病中获得性单亲二体与纯合基因突变之间的关联。
Cancer Res. 2005 Oct 15;65(20):9152-4. doi: 10.1158/0008-5472.CAN-05-2017.
3
Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis.采用高分辨率单核苷酸多态性分析技术鉴定细胞遗传学正常的急性髓系白血病中的获得性拷贝数改变和单亲二体性。
Leukemia. 2010 Feb;24(2):438-49. doi: 10.1038/leu.2009.263. Epub 2009 Dec 17.
4
Combined testing for CCAAT/enhancer-binding protein alpha (CEBPA) mutations and promoter methylation in acute myeloid leukemia demonstrates shared phenotypic features.急性髓系白血病中 CCAAT/增强子结合蛋白α(CEBPA)突变和启动子甲基化的联合检测显示出共同的表型特征。
Leuk Res. 2011 Feb;35(2):200-7. doi: 10.1016/j.leukres.2010.09.018. Epub 2010 Oct 20.
5
Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype.单亲二体可能与核型正常的急性髓系白血病(AML)中的微卫星不稳定性相关。
Leuk Lymphoma. 2008 Jun;49(6):1178-83. doi: 10.1080/10428190802035941.
6
K313dup is a recurrent CEBPA mutation in de novo acute myeloid leukemia (AML).K313dup是初发急性髓系白血病(AML)中一种常见的CEBPA基因突变。
Ann Hematol. 2008 Oct;87(10):819-27. doi: 10.1007/s00277-008-0528-2. Epub 2008 Jun 28.
7
Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia.节段性单亲二体是复发性急性髓系白血病中常见的获得性遗传事件。
Blood. 2008 Aug 1;112(3):814-21. doi: 10.1182/blood-2008-01-132431. Epub 2008 May 19.
8
Somatic CEBPA mutations are a frequent second event in families with germline CEBPA mutations and familial acute myeloid leukemia.在具有胚系CEBPA突变和家族性急性髓系白血病的家族中,体细胞CEBPA突变是常见的继发事件。
J Clin Oncol. 2008 Nov 1;26(31):5088-93. doi: 10.1200/JCO.2008.16.5563. Epub 2008 Sep 2.
9
Complexity of CEBPA dysregulation in human acute myeloid leukemia.人类急性髓系白血病中CEBPA失调的复杂性
Clin Cancer Res. 2009 Sep 1;15(17):5303-7. doi: 10.1158/1078-0432.CCR-08-2941. Epub 2009 Aug 25.
10
Role of CEBPA in normal karyotype acute myeloid leukemia.CEBPA在正常核型急性髓系白血病中的作用
J Clin Oncol. 2009 Apr 20;27(12):2105; author reply 2106. doi: 10.1200/JCO.2008.21.5418. Epub 2009 Mar 9.

引用本文的文献

1
Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations.散发性和家族性伴有 CEBPA 突变的急性髓系白血病。
Curr Hematol Malig Rep. 2023 Oct;18(5):121-129. doi: 10.1007/s11899-023-00699-3. Epub 2023 Jun 1.
2
Germline CEBPA mutation in familial acute myeloid leukemia.家族性急性髓系白血病中的胚系CEBPA突变
Hematol Rep. 2021 Oct 4;13(3):9114. doi: 10.4081/hr.2021.9114. eCollection 2021 Sep 6.
3
Variable outcome and methylation status according to mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment.
双突变急性髓系白血病患者根据突变类型的可变预后和甲基化状态及其对治疗的可能影响。
Haematologica. 2018 Jan;103(1):91-100. doi: 10.3324/haematol.2017.173096. Epub 2017 Oct 12.
4
Utility of a Direct 16S rDNA PCR and Sequencing for Etiological Diagnosis of Infective Endocarditis.16S rDNA 直接 PCR 和测序在感染性心内膜炎病因诊断中的应用。
Ann Lab Med. 2017 Nov;37(6):505-510. doi: 10.3343/alm.2017.37.6.505.
5
The role of different genetic subtypes of CEBPA mutated AML.CEBPA 基因突变的不同基因亚型在 AML 中的作用。
Leukemia. 2014 Apr;28(4):794-803. doi: 10.1038/leu.2013.273. Epub 2013 Sep 23.
6
Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer.乳腺癌中获得性单亲二体性和纯合突变与 HER2/ER/PR 状态的关系。
PLoS One. 2010 Nov 30;5(11):e15094. doi: 10.1371/journal.pone.0015094.
7
New lesions detected by single nucleotide polymorphism array-based chromosomal analysis have important clinical impact in acute myeloid leukemia.基于单核苷酸多态性阵列的染色体分析检测到的新病变对急性髓系白血病具有重要的临床影响。
J Clin Oncol. 2009 Nov 1;27(31):5219-26. doi: 10.1200/JCO.2009.21.9840. Epub 2009 Sep 21.
8
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms.与骨髓增生异常/骨髓增殖性肿瘤相关的4q24杂合性缺失和TET2突变
Blood. 2009 Jun 18;113(25):6403-10. doi: 10.1182/blood-2009-02-205690. Epub 2009 Apr 16.
9
Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome.双CEBPA突变而非单CEBPA突变定义了急性髓系白血病的一个亚组,该亚组具有独特的基因表达谱,且与良好预后唯一相关。
Blood. 2009 Mar 26;113(13):3088-91. doi: 10.1182/blood-2008-09-179895. Epub 2009 Jan 26.
10
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects.急性髓系白血病全基因组基因表达谱分析十年:回顾与展望
Blood. 2009 Jan 8;113(2):291-8. doi: 10.1182/blood-2008-04-153239. Epub 2008 Aug 14.