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支顶孢属椎骨骨髓炎：分子诊断及对伏立康唑的反应

Acremonium vertebral osteomyelitis: molecular diagnosis and response to voriconazole.

作者信息

Keynan Yoav, Sprecher Hannah, Weber Gabriel

机构信息

Department of Medicine, Infectious Diseases Unit, Carmel Medical Center, Haifa, Israel.

出版信息

Clin Infect Dis. 2007 Jul 1;45(1):e5-6. doi: 10.1086/518700. Epub 2007 May 23.

DOI:10.1086/518700
PMID:17554690
Abstract

We present a case of Acremonium vertebral osteomyelitis that relapsed despite surgical debridement and prolonged treatment with liposomal amphotericin B, but which responded to voriconazole therapy. The report highlights the role of molecular diagnosis of rare fungal osteomyelitis. The patient was successfully treated with voriconazole.

摘要

我们报告一例顶孢霉性脊椎骨髓炎病例，尽管进行了手术清创并长期使用脂质体两性霉素B治疗，但仍复发，不过对伏立康唑治疗有反应。该报告强调了罕见真菌性骨髓炎分子诊断的作用。患者接受伏立康唑治疗成功。

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