Sinbawy A, McDonnell P J, Moreira H
Doheny Eye Institute, Los Angeles, CA 90033.
Arch Ophthalmol. 1991 Nov;109(11):1531-3. doi: 10.1001/archopht.1991.01080110067036.
Excimer laser corneal ablation (photorefractive keratectomy) for myopia using a diaphragm delivery system was performed on eye bank and animal eyes by either progressively expanding or contracting the iris aperture. Use of an expanding aperture, in which the final ablations cover the entire treatment zone, produced a pseudomembrane over the zone that had few discontinuities. Ultrastructural examination of the corneas ablated using a progressively contracting aperture, however, revealed numerous discontinuities in the surface pseudomembrane. Use of an expanding iris aperture to perform ablations to correct myopia may be preferable as it produces a pseudomembrane with few discontinuities. Clinical studies of surface healing in humans are necessary to determine the clinical relevance of improved continuity of the surface pseudomembrane.
使用光阑输送系统，通过逐渐扩大或收缩虹膜孔径，在眼库和动物眼睛上进行准分子激光角膜消融术（屈光性角膜切削术）治疗近视。使用扩大孔径，最终消融覆盖整个治疗区域，在该区域产生了几乎没有间断的假膜。然而，对使用逐渐收缩孔径进行消融的角膜进行超微结构检查时，发现表面假膜存在大量间断。使用扩大的虹膜孔径进行消融以矫正近视可能更可取，因为它产生的假膜间断较少。需要对人类表面愈合进行临床研究，以确定表面假膜连续性改善的临床相关性。
