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真菌性神经感染:罕见疾病但死亡率高得令人无法接受。

Fungal neuroinfections: rare disease but unacceptably high mortality.

作者信息

Njambi S, Huttova M, Kovac M, Freybergh P F, Bauer F, Muli J M

机构信息

Tropical programmes of St. Elizabeth College of Health and Social Sciences in Eldovel, Kenya and Jiima, Ethiopia.

出版信息

Neuro Endocrinol Lett. 2007 Jun;28 Suppl 2:25-6.

PMID:17558372
Abstract

Within last 25 years we have observed 20 cases of fungal meningitis and/or cerebral abscesses. Commonest etiologic agens was Candida spp. (C. albicans 9 of 20). Molds were responsible for 4 cases of brain abscess. Mortality was 50% what seems to be very high. Extremely high mortality is caused by delayed onset of therapy, severe underlying disease and multiresistant fungal organisms such as Mucorales, Fusarium solani and Aureobasidium.

摘要

在过去25年里,我们观察到20例真菌性脑膜炎和/或脑脓肿病例。最常见的病原体是念珠菌属(20例中有9例为白色念珠菌)。霉菌导致了4例脑脓肿。死亡率为50%,这似乎非常高。极高的死亡率是由治疗延迟、严重的基础疾病以及诸如毛霉目、茄病镰刀菌和 Aureobasidium 等多重耐药真菌引起的。

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Neuro Endocrinol Lett. 2007 Jun;28 Suppl 2:25-6.
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Fungal brain abscesses caused by species.由[具体物种]引起的真菌性脑脓肿。 (你提供的原文中“species”前缺少具体物种名称,翻译只能到此为止)
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