Zhu Zifeng, Huang Zhehao, Li Zhenshengnan, Li Xianglan, Du Chao, Tian Yu
Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Department of Clinical Medicine, Norman Bethune Health Science Center of Jilin University, Changchun, Jilin 130021, P.R. China.
Exp Ther Med. 2018 Mar;15(3):2374-2380. doi: 10.3892/etm.2018.5692. Epub 2018 Jan 4.
The present case report described the initial diagnosis of a 25-year old female with a brain abscess consisting of two lesions 0.2 and 2.9 cm in volume. The patient was initially treated with antibiotics; however, 2 months following initial treatment, the patient's condition deteriorated and she became vegetative. Following transfer to the China-Japan Union Hospital of Jilin University (Jilin, China) the two lesions had grown in volume to 9.0 and 13.0 cm, respectively. The results of magnetic resonance spectroscopy and plasma 1-3-β-D-glucan activity suggested a possible fungal infection. Subsequently, a stereotactic biopsy was conducted, fluid was cultured and itraconazole treatment was initiated. Analysis of cultures confirmed a infection and antifungal treatment was continued. Shortly following surgery, the patient regained consciousness and the ability to eat and speak. A follow-up MRI 8 months following biopsy confirmed disappearance of all lesions and no recurrence. To the best of our knowledge, this is the first English-language report of a brain abscess caused primarily by .
本病例报告描述了一名25岁女性脑脓肿的初步诊断情况，该脑脓肿由两个体积分别为0.2厘米和2.9厘米的病灶组成。患者最初接受了抗生素治疗；然而，初始治疗2个月后，患者病情恶化并进入植物人状态。转至吉林大学中日联谊医院（中国吉林）后，两个病灶的体积分别增大至9.0厘米和13.0厘米。磁共振波谱分析和血浆1-3-β-D-葡聚糖活性检测结果提示可能存在真菌感染。随后进行了立体定向活检，对液体进行培养并开始使用伊曲康唑治疗。培养分析证实了感染，继续进行抗真菌治疗。手术后不久，患者恢复意识，具备进食和说话能力。活检8个月后的随访磁共振成像证实所有病灶消失且无复发。据我们所知，这是第一份主要由……引起的脑脓肿的英文报告。 （注：原文中“a infection”表述有误，可能影响准确理解，这里按原样翻译）
