Oomen Joannes L T, Cuesta Miguel A, Engel Alexander F
Department of Surgery, Zaans Medical Centre, Zaandam, The Netherlands.
Scand J Gastroenterol. 2007 Jul;42(7):841-7. doi: 10.1080/00365520601113810.
To compare POSSUM, p-POSSUM, and cr-POSSUM-predicted mortalities with the observed postoperative mortality in patients undergoing elective sigmoid colectomy for diverticular disease (n=121) or carcinoma (n=120).
The physiologic and operative severity score for the enumeration of mortality and morbidity (POSSUM) was used to identify patient- or disease-related risk factors and to calculate expected mortalities.
Patients with carcinoma had significantly higher POSSUM scores, but the observed mortality (1.7%) was lower than that in the diverticular disease group (3.3%). In the carcinoma group, mortality was over-predicted by all the POSSUM systems. In diverticular disease, POSSUM over-predicted mortality while p-POSSUM and cr-POSSUM under-predicted mortality. In the whole group, POSSUM over-predicted mortality. P-POSSUM and cr-POSSUM predicted mortality accurately: observed:expected (O:E) ratio 0.83. Replacing the score for malignancy with a minimum score of 1 gave overall O:E ratios of 0.37 (POSSUM), 1.04 (p-POSSUM), and 0.93 (cr-POSSUM).
In a group of patients who underwent elective resection of the sigmoid colon for carcinoma or diverticular disease, postoperative mortality was predicted accurately by p-Possum and cr-POSSUM, especially when used without a score for malignancy. None of the POSSUM scores were predictive of disease-specific mortality.
比较朴索姆(POSSUM)、改良朴索姆(p-POSSUM)和结肠直肠朴索姆(cr-POSSUM)预测的死亡率与择期行乙状结肠切除术治疗憩室病(n = 121)或癌(n = 120)患者的术后观察死亡率。
采用用于计算死亡率和发病率的生理与手术严重程度评分系统(POSSUM)来识别患者或疾病相关风险因素并计算预期死亡率。
癌症患者的POSSUM评分显著更高,但观察到的死亡率(1.7%)低于憩室病组(3.3%)。在癌症组中,所有POSSUM系统均高估了死亡率。在憩室病中,POSSUM高估了死亡率,而p-POSSUM和cr-POSSUM低估了死亡率。在整个组中,POSSUM高估了死亡率。P-POSSUM和cr-POSSUM准确预测了死亡率:观察值与预期值(O:E)之比为0.83。将恶性肿瘤评分替换为最低分为1的评分后,总体O:E比值分别为0.37(POSSUM)、1.04(p-POSSUM)和0.93(cr-POSSUM)。
在一组因癌症或憩室病接受择期乙状结肠切除术的患者中,p-Possum和cr-POSSUM能准确预测术后死亡率,尤其是在不使用恶性肿瘤评分时。没有一个POSSUM评分能够预测疾病特异性死亡率。