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一种用于预测急诊结直肠手术死亡率的新型简化评分系统:预测模型的开发

A novel simplified scoring system for predicting mortality in emergency colorectal surgery: prediction model development.

作者信息

Er Sadettin, Sevim Yusuf, Özden Sabri, Tikici Deniz, Yıldız Barış Doğu, Yüksel Bülent Cavit, Turan Umut Fırat, Tez Mesut

机构信息

MD. Attending Physician, Department of Surgery, Ankara Numune Eğitim ve Araştırma Hastanesi, Ankara, Turkey.

MD. Associate Professor, Department of Surgery, Ankara Numune Eğitim ve Araştırma Hastanesi, Ankara, Turkey.

出版信息

Sao Paulo Med J. 2019 Jul 15;137(2):132-136. doi: 10.1590/1516-3180.2018.0316240119.

DOI:10.1590/1516-3180.2018.0316240119
PMID:31314873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9721224/
Abstract

BACKGROUND

Despite advances in surgical approaches, emergency colorectal surgery has high mortality and morbidity.

OBJECTIVE

We aimed to create a simple and distinctive scoring system, for predicting mortality among patients undergoing emergency colorectal surgery.

DESIGN AND SETTING

Prediction model development study based on retrospective data-gathering.

METHODS

Patients who underwent emergency colorectal surgery between March 2014 and December 2016 at a single tertiary-level referral center were included in our study. Patient demographics, comorbidities, type of surgery, etiology and laboratory and radiological findings were collected retrospectively and analyzed. A new clinical score (named the Numune emergency colorectal resection score) was constructed from the last logistic regression model, in which one point was assigned for the presence of each predictive factor.

RESULTS

138 patients underwent emergency colorectal surgery. These comprised 64 males (46.4%) and 74 females (53.6%), with a mean age of 64 years. Multivariate analysis revealed that blood urea nitrogen level > 65 mg/dl (odds ratio, OR: 8.03; 95% confidence interval, CI: 2.16-15.77), albumin level < 0.7 -mg/-dl (OR: 4.43; 95% CI: 1.96-14.39) and American Society of Anesthesiologists score ≥ 3 (OR: 3.47; 95% CI: 0.81-9.18) were associated with postoperative complications. The Numune score was graded from I to III. The risk of mortality was found to be 63.2% in the group with grade III, which accounted for 35.2% of the subjects. There were 37 postoperative deaths.

CONCLUSIONS

Surgeons need scoring systems, especially to predict postoperative mortality. We propose the Numune emergency colorectal resection score for emergency surgical procedures as a practical, usable and effective system for predicting postoperative morbidity.

摘要

背景

尽管手术方法有所进步,但急诊结直肠手术的死亡率和发病率仍很高。

目的

我们旨在创建一个简单且独特的评分系统,用于预测接受急诊结直肠手术患者的死亡率。

设计与背景

基于回顾性数据收集的预测模型开发研究。

方法

纳入2014年3月至2016年12月在一家三级转诊中心接受急诊结直肠手术的患者。回顾性收集并分析患者的人口统计学资料、合并症、手术类型、病因以及实验室和影像学检查结果。根据最后一个逻辑回归模型构建了一个新的临床评分(命名为努姆内急诊结直肠切除评分),每个预测因素存在则计1分。

结果

138例患者接受了急诊结直肠手术。其中男性64例(46.4%),女性74例(53.6%),平均年龄64岁。多因素分析显示,血尿素氮水平>65mg/dl(比值比,OR:8.03;95%置信区间,CI:2.16 - 15.77)、白蛋白水平<0.7mg/dl(OR:4.43;95%CI:1.96 - 14.39)以及美国麻醉医师协会评分≥3(OR:3.47;95%CI:0.81 - 9.18)与术后并发症相关。努姆内评分分为I至III级。III级组的死亡率为63.2%,该组占受试者的35.2%。术后有37例死亡。

结论

外科医生需要评分系统,尤其是用于预测术后死亡率。我们提出将努姆内急诊结直肠切除评分用于急诊手术,作为预测术后发病率的实用、可用且有效的系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9b3/9721224/a09cf1a42619/1806-9460-spmj-137-02-132-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9b3/9721224/a09cf1a42619/1806-9460-spmj-137-02-132-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9b3/9721224/a09cf1a42619/1806-9460-spmj-137-02-132-gf1.jpg

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本文引用的文献

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Colorectal Dis. 2014 Aug;16(8):631-9. doi: 10.1111/codi.12580.
2
Development and evaluation of the universal ACS NSQIP surgical risk calculator: a decision aid and informed consent tool for patients and surgeons.开发和评估通用 ACS NSQIP 手术风险计算器:为患者和外科医生提供的决策辅助和知情同意工具。
J Am Coll Surg. 2013 Nov;217(5):833-42.e1-3. doi: 10.1016/j.jamcollsurg.2013.07.385. Epub 2013 Sep 18.
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Elderly POSSUM, a dedicated score for prediction of mortality and morbidity after major colorectal surgery in older patients.
老年 POSSUM,一种专门用于预测老年患者大结肠手术后死亡率和发病率的评分。
Br J Surg. 2010 Mar;97(3):396-403. doi: 10.1002/bjs.6903.
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Postoperative medical complications are the main cause of early death after emergency surgery for colonic cancer.术后医疗并发症是结肠癌急诊手术后早期死亡的主要原因。
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Population-based information on emergency colorectal surgery and evaluation on effect of operative volume on mortality.基于人群的急诊结直肠手术信息及手术量对死亡率影响的评估。
World J Surg. 2008 Sep;32(9):2077-82. doi: 10.1007/s00268-008-9632-7.
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Comparison of outcome of POSSUM, p-POSSUM, and cr-POSSUM scoring after elective resection of the sigmoid colon for carcinoma or complicated diverticular disease.对因癌或复杂性憩室病行乙状结肠择期切除术后 POSSUM、p-POSSUM 和 cr-POSSUM 评分结果的比较。
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Outcome of acutely perforated colorectal cancers: experience of a single district general hospital.急性穿孔性结直肠癌的治疗结果:一家区级综合医院的经验
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Dis Colon Rectum. 2006 Jun;49(6):816-24. doi: 10.1007/s10350-006-0523-4.
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Comparative study of left colonic Peritonitis Severity Score and Mannheim Peritonitis Index.左半结肠腹膜炎严重程度评分与曼海姆腹膜炎指数的比较研究。
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