在分子氧存在下，氯化钌（III）中-四苯基卟啉催化硫化物选择性氧化为亚砜。

Selective oxidation of sulfides to sulfoxides catalyzed by ruthenium (III) meso-tetraphenylporphyrin chloride in the presence of molecular oxygen.

作者信息

Zhou Xian-Tai, Ji Hong-Bing, Cheng Zhao, Xu Jian-Chang, Pei Li-Xia, Wang Le-Fu

机构信息

School of Chemical and Energy Engineering, South China University of Technology, Guangzhou 510640, China.

出版信息

Bioorg Med Chem Lett. 2007 Aug 15;17(16):4650-3. doi: 10.1016/j.bmcl.2007.05.073. Epub 2007 May 26.

DOI:10.1016/j.bmcl.2007.05.073

PMID:17560784

Abstract

Highly efficient selective oxidation of sulfides to sulfoxides by molecular oxygen catalyzed by ruthenium (III) meso-tetraphenylporphyrin chloride (Ru(TPP)Cl) with isobutyraldehyde as oxygen acceptor has been reported. In large-scale experiment of thioanisole oxidation, the isolated yield of sulfoxide of 92% was obtained and the turnover number reached up to 92,000.

摘要

据报道，以异丁醛作为氧受体，由氯化钌（III）中-四苯基卟啉（Ru(TPP)Cl）催化，分子氧可将硫化物高效选择性氧化为亚砜。在苯甲硫醚氧化的大规模实验中，亚砜的分离产率达到92%，周转数高达92000。