在温和条件下无过渡金属高效有氧氧化硫化物为亚砜。

State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, No.158-139, Zhongshan Road, Dalian 116012, China.

Molecules. 2009 Dec 28;15(1):83-92. doi: 10.3390/molecules15010083.

A highly efficient transition-metal-free catalytic system Br2/NaNO2/H2O has been developed for a robust and economic acid-free aerobic oxidation of sulfides. It is noteworthy that the sulfide function reacts under mild conditions without over-oxidation to sulfone. The role of NaNO2as an efficient NO equivalent for the activation of molecular oxygen was identified. Under the optimal conditions, a broad range of sulfide substrates were converted into their corresponding sulfoxides in high yields by molecular oxygen. The present catalytic system utilizes cheap and readily available agents as the catalysts, exhibits high selectivity for sulfoxide products and releases only innocuous water as the by-products.

一种高效的无过渡金属催化体系 Br2/NaNO2/H2O 已被开发用于在酸性条件下温和、经济地实现亚砜的有氧氧化。值得注意的是，该反应体系中亚砜的选择性高，不会过度氧化为砜。该体系中亚硝酸盐作为高效的氮氧等价物可以有效地活化分子氧。在最优条件下，该催化体系可以利用氧气作为氧化剂，以高收率将多种硫醚转化为相应的亚砜产物，且所用的催化剂廉价易得，反应条件温和，产物选择性高，仅生成无害的水作为副产物。