Sternberg David I, Sonett Joshua R
Section of Thoracic Surgery, Columbia University Medical Center, New-York Presbyterian Hospital, New York, NY 10032, USA.
Semin Oncol. 2007 Jun;34(3):186-96. doi: 10.1053/j.seminoncol.2007.03.004.
Almost 125 years after the first documented case, pulmonary metastasectomy is still poorly understood. No other organ is subject to the wide histologic variety of metastatic insults, and this fact has complicated a complete exposition of when pulmonary metastasectomy may be beneficial. Many physicians still consider pulmonary metastatic disease to be always incurable, and they may underestimate existing surgical options including the benefits of pulmonary metastasectomy. In addition, technological improvements in radiological screening of pulmonary metastases and thoracoscopic resection are fundamentally altering the management of these patients and their surgery. This article reviews the history, form, and future of pulmonary metastasectomy, the literature that supports or refutes its application in various tumor types, and the screening and surgical evaluation that is needed prior to its performance.
在首例有记录的病例出现近125年后，肺转移瘤切除术仍未得到充分理解。没有其他器官会受到如此广泛的组织学转移性损伤，这一事实使得全面阐述肺转移瘤切除术何时可能有益变得复杂。许多医生仍然认为肺转移性疾病总是无法治愈的，他们可能低估了现有的手术选择，包括肺转移瘤切除术的益处。此外，肺转移瘤的放射学筛查和胸腔镜切除术的技术进步正在从根本上改变这些患者的治疗和手术方式。本文回顾了肺转移瘤切除术的历史、形式和未来，支持或反驳其在各种肿瘤类型中应用的文献，以及在进行该手术之前所需的筛查和手术评估。
