Mangiameli Giuseppe, Cioffi Ugo, Alloisio Marco, Testori Alberto
Division of Thoracic Surgery, IRCCS Humanitas Research Hospital, Milan, Italy.
Department of Biomedical Sciences, Humanitas University, Milan, Italy.
Front Surg. 2022 Apr 29;9:884915. doi: 10.3389/fsurg.2022.884915. eCollection 2022.
Pulmonary metastasectomy is an established treatment that can provide improved long- term survival for patients with metastatic tumor(s) in the lung. In this mini-review, we discuss the state of the art of thoracic surgery in surgical management of lung metastases which actually occurs for a large part of surgical activity in thoracic surgery department. We describe the principles of surgical therapy that have been defined across the time, and that should remain the milestones of lung metastases treatment: a radical surgery and an adequate lymphadenectomy. We then focus on current surgical indications and report the oncological results according to the surgical approach (open vs. mini-invasive), the histological type and number of lung metastases, and in case of re-metastasectomy. Finally, we conclude with a brief overview about the future perspectives in thoracic surgery in treatment of lung metastases.
肺转移瘤切除术是一种成熟的治疗方法，可为肺部有转移性肿瘤的患者提供更长的生存期。在本综述中，我们讨论了胸外科手术治疗肺转移瘤的最新技术，实际上这在胸外科的大部分手术活动中都有发生。我们描述了随着时间推移所确定的手术治疗原则，这些原则应始终是肺转移瘤治疗的里程碑：根治性手术和充分的淋巴结清扫术。然后，我们重点关注当前的手术适应症，并根据手术方式（开放手术与微创手术）、肺转移瘤的组织学类型和数量以及再次进行转移瘤切除术的情况报告肿瘤学结果。最后，我们简要概述了胸外科在治疗肺转移瘤方面的未来前景。
