Vazquez Bianca, Rousseau Dennis, Hurd Thelma C
Department of Surgery, University of Texas Health Sciences Center at San Antonio, San Antonio, TX, USA.
Semin Oncol. 2007 Jun;34(3):234-40. doi: 10.1053/j.seminoncol.2007.03.013.
Breast cancer treatment outcomes have improved as a result of early detection and multidisciplinary treatment approaches. Treatment options continue to expand as understanding increases regarding the relationship between disease burden, biology, and outcome. In this article we present the current principles and challenges that face the clinician who is treating breast disease. Better understanding of the biology of high-risk lesions and the significance of minimal metastatic disease permits better treatment. Advances in reconstructive surgery, continued refinement of resection techniques, and the management of less common presentations of breast cancer are presented.
由于早期检测和多学科治疗方法，乳腺癌的治疗效果有所改善。随着对疾病负担、生物学和治疗结果之间关系的认识不断增加，治疗选择也在不断扩大。在本文中，我们阐述了治疗乳腺疾病的临床医生目前面临的原则和挑战。对高危病变生物学特性的更好理解以及微小转移疾病的意义有助于更好的治疗。本文还介绍了重建手术的进展、切除技术的持续改进以及乳腺癌较少见表现的管理。
