DeZee Kent J, Hatzigeorgiou Christos, Kristo David, Jackson Jeffrey L
Walter Reed Army Medical Center, Washington, DC, USA.
J Clin Sleep Med. 2005 Apr 15;1(2):136-42.
Patients seen in sleep clinics have been reported to have a high prevalence of mental disorders, but there is no recommended method for screening. We sought to assess the prevalence of mental disorders, using a validated screening instrument, among referrals to a sleep clinic and to determine whether referred patients with mental disorders were less likely to have an underlying diagnosis of sleep-disordered breathing.
Consecutive adult new referrals to a sleep clinic at a tertiary care center were invited to participate in this cross-sectional assessment of mental and sleep disorders. All patients were screened for mental disorders with the Primary Care Evaluation of Mental Disorders prior to their appointment with the sleep provider. Sleep disorders were diagnosed as per the sleep provider's judgment, usually by polysomnography.
From 217 invited participants, 171 completed the survey and could be linked to clinical data. Eighty-one percent underwent polysomnography, and most (83%) had a diagnosis of sleep-disordered breathing. Thirty-eight patients (22%) had at least 1 mental disorder, and 17 (10%) had 2. Eleven percent of patients had major depression, 7% minor depression, 3% panic disorder, and 12% anxiety not otherwise specified. Patients with an underlying mental disorder were significantly less likely to have a diagnosis of sleep-disordered breathing, compared to those without an underlying mental disorder (66% vs 87%, P = .004).
MMPI, Minnesota Multiphasic Personality Inventory; MOS SF-6, Multiple Outcomes Study Short Form 6; OSA, Obstructive sleep apnea; PHQ-9, Patient Health Questionnaire-9; PHQ-15, Patient Health Questionnaire-15; PRIME-MD, Primary Care Evaluation of Mental Disorders; RDI, Respiratory Disturbance Index; SCL-90, Symptom Distress Check List.
Mental disorders are common in adults referred to sleep clinics. Those with a mental disorder are less likely to have a diagnosis of sleep-disordered breathing. A negative sleep study should prompt clinicians to consider possible underlying psychiatric disease.
据报道,睡眠诊所的患者中精神障碍患病率较高,但尚无推荐的筛查方法。我们试图使用经过验证的筛查工具,评估转诊至睡眠诊所的患者中精神障碍的患病率,并确定患有精神障碍的转诊患者被诊断为睡眠呼吸障碍的可能性是否较低。
邀请一家三级医疗中心睡眠诊所的连续成年新转诊患者参与这项精神和睡眠障碍的横断面评估。所有患者在预约睡眠专家之前,均使用《初级保健精神障碍评估量表》进行精神障碍筛查。睡眠障碍根据睡眠专家的判断进行诊断,通常通过多导睡眠图进行诊断。
在217名受邀参与者中,171人完成了调查并可与临床数据相关联。81%的人接受了多导睡眠图检查,大多数(83%)被诊断为睡眠呼吸障碍。38名患者(22%)至少患有一种精神障碍,17名(10%)患两种精神障碍。11%的患者患有重度抑郁症,7%患有轻度抑郁症,3%患有惊恐障碍,12%患有未另行规定的焦虑症。与没有潜在精神障碍的患者相比,患有潜在精神障碍的患者被诊断为睡眠呼吸障碍的可能性显著较低(66%对87%,P = 0.004)。
MMPI,明尼苏达多相人格调查表;MOS SF-6,简明健康调查简表6;OSA,阻塞性睡眠呼吸暂停;PHQ-9,患者健康问卷9;PHQ-15,患者健康问卷15;PRIME-MD,初级保健精神障碍评估量表;RDI,呼吸紊乱指数;SCL-90,症状困扰检查表。
转诊至睡眠诊所的成年人中精神障碍很常见。患有精神障碍的人被诊断为睡眠呼吸障碍的可能性较小。睡眠研究结果为阴性时,临床医生应考虑可能存在的潜在精神疾病。