Coquelin A
Department of Cell Biology and Anatomy, Texas Tech University Health Sciences Center, Lubbock 79430.
Biol Reprod. 1991 Nov;45(5):680-4. doi: 10.1095/biolreprod45.5.680.
In contrast to other male mice, many hybrid B6D2F1 males continue to mate after being castrated in adulthood. This persistent sexual behavior in the castrated hybrids presumably is based upon heterozygosity that might occur within individual loci or between different loci. Those possibilities were discriminated by studying BXD recombinant inbred mice. In BXD strains, individual loci are homozygous, but heterozygosity has arisen between separate loci. Males in two of six BXD strains persisted in copulating for 5 mo after being castrated. Thus, it is concluded that retention of masculine sexual behavior in castrated mice is a function of heterozygosity between loci.
与其他雄性小鼠不同，许多杂种B6D2F1雄性小鼠在成年后被阉割后仍继续交配。阉割后的杂种小鼠这种持续的性行为大概是基于个体基因座内或不同基因座之间可能出现的杂合性。通过研究BXD重组近交系小鼠来区分这些可能性。在BXD品系中，个体基因座是纯合的，但不同基因座之间出现了杂合性。六个BXD品系中有两个品系的雄性在被阉割后仍持续交配5个月。因此，可以得出结论，阉割后小鼠雄性性行为的保留是基因座间杂合性的一种表现。
