McGill T E, Manning A
Anim Behav. 1976 Aug;24(3):507-18. doi: 10.1016/s0003-3472(76)80063-2.
Genotype proves to be an important factor affecting the retention of sexual responsiveness following castration. Male F1 hybrids between C57BL/6 females and DBA/2 males (B6D2F1) show very prolonged retention. Experiment 1 used a diallelic design using C57BL/6, DBA/2 and BALB/c strains and showed that heterosis per se is not an adequate explanation of the superior retention of the B6D2F1 genotype. Experiment 2 showed that neonatal injections of 100 mug TP to B6D2F1 male mice did not result in better retention of the ejaculatory reflex after castration in adulthood. B6D2F1 males from both experiments who exhibited the ejaculatory reflex for many months after castration went through a 'difficult period' in the first 10 to 12 postcastration weeks. During this time, ejaculation latency increased fourfold, and then returned to the original level. On the other hand, the proportion of males reaching the ejaculatory threshold during this period first declined then increased.
基因型被证明是影响去势后性反应保留的一个重要因素。C57BL/6雌性与DBA/2雄性的雄性F1杂种（B6D2F1）表现出非常长时间的保留。实验1采用了使用C57BL/6、DBA/2和BALB/c品系的双等位基因设计，并表明杂种优势本身并不能充分解释B6D2F1基因型的优越保留。实验2表明，在成年去势后，给B6D2F1雄性小鼠新生期注射100微克睾酮并不能更好地保留射精反射。来自两个实验的B6D2F1雄性小鼠在去势后数月仍表现出射精反射，在去势后的前10至12周经历了一个“困难时期”。在此期间，射精潜伏期增加了四倍，然后恢复到原来的水平。另一方面，在此期间达到射精阈值的雄性比例先下降后上升。
