Calhoun Patrick S, Dennis Michelle F, Beckham Jean C
Veterans Affairs Medical Center, Durham, NC 27705, USA.
Exp Clin Psychopharmacol. 2007 Jun;15(3):256-63. doi: 10.1037/1064-1297.15.3.256.
The present study examined whether reactivity to emotional stressors is related to early relapse from smoking cessation in persons with posttraumatic stress disorder (PTSD). Smokers with PTSD who had failed to sustain any previous quit attempt for 7 days (n=26) and PTSD smokers who were able to sustain a quit attempt for more than a week (n=50) were exposed to emotional stimuli in the form of personalized scripts that included neutral/relaxing experiences, stressful/nontraumatic experiences, and traumatic experiences. Results indicated an interaction between script type and group. Although groups did not differ after presentation of neutral scripts, persons with PTSD unable to sustain a quit attempt for as long as 7 days responded with greater levels of emotional reactivity to both stressful and trauma stimuli relative to those able to sustain a quit attempt longer than 7 days. Further, results suggested that emotional reactivity to stressors (both traumatic and nontraumatic) is related to duration of past longest quit attempt in smokers with PTSD. Results are consistent with findings in nonpsychiatric samples that suggest that individual differences in affective regulatory processes are related to duration of smoking cessation attempts. Systematic replications including a prospective design are recommended.
本研究探讨了创伤后应激障碍(PTSD)患者对情绪应激源的反应性是否与戒烟早期复发有关。曾有过戒烟尝试但未能持续7天的PTSD吸烟者(n = 26)以及能够持续戒烟尝试超过一周的PTSD吸烟者(n = 50),被暴露于以个性化脚本形式呈现的情绪刺激中,这些脚本包括中性/放松体验、应激/非创伤性体验以及创伤性体验。结果表明脚本类型与组别之间存在交互作用。尽管在呈现中性脚本后两组没有差异,但与能够持续戒烟尝试超过7天的人相比,未能持续戒烟尝试长达7天的PTSD患者对压力和创伤刺激的情绪反应水平更高。此外,结果表明,PTSD吸烟者对应激源(包括创伤性和非创伤性)的情绪反应性与过去最长戒烟尝试的持续时间有关。这些结果与非精神科样本中的研究结果一致,即情感调节过程中的个体差异与戒烟尝试的持续时间有关。建议进行包括前瞻性设计的系统重复研究。