Persons D L, Bridge J A, Neff J R
Department of Pathology and Oncology, University of Kansas Medical Center.
Cancer Genet Cytogenet. 1991 Oct 15;56(2):197-201. doi: 10.1016/0165-4608(91)90171-p.
Cytogenetic analysis of two sacral chordomas revealed two distinct abnormal clones in one of the cases: 44,XY,t(1;3)(q42;q11), -2,der(7)t(2;7)(q23;q32), -21 and 46,X,t(Y;8)(q12;q22), t(1;14)(p34;q32),t(5;10)(q13;p11). All cells analyzed from the second case were cytogenetically normal. To the best of our knowledge, chordomas have not previously been subjected to cytogenetic analysis.
对两例骶骨脊索瘤进行的细胞遗传学分析显示，其中一例存在两个不同的异常克隆：44,XY,t(1;3)(q42;q11), -2,der(7)t(2;7)(q23;q32), -21以及46,X,t(Y;8)(q12;q22), t(1;14)(p34;q32),t(5;10)(q13;p11)。第二例分析的所有细胞在细胞遗传学上均正常。据我们所知，此前尚未对脊索瘤进行过细胞遗传学分析。
