Kaste Sue C, Rodriguez-Galindo Carlos, McCarville Mary E, Shulkin Barry L
Division of Diagnostic Imaging, Department of Radiological Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105-2794, USA.
Pediatr Radiol. 2007 Jul;37(7):615-22. doi: 10.1007/s00247-007-0467-4. Epub 2007 May 22.
Our objective was to assess the utility of PET-CT in five pediatric patients with Langerhans cell histiocytosis (LCH) who underwent PET-CT imaging for clinical staging and determination of lesion activity at various stages of treatment and follow-up. PET-CT combines the anatomic detail of CT and the physiologic activity of (18)F-FDG imaging. We conclude that PET-CT information is clinically useful to evaluate disease activity and response to therapy and provides information that cannot be obtained from technetium 99m methylene diphosphonate bone scans or radiographs.
我们的目的是评估正电子发射断层扫描-计算机断层扫描（PET-CT）在5例朗格汉斯细胞组织细胞增多症（LCH）患儿中的应用价值，这些患儿接受PET-CT成像以进行临床分期，并确定治疗及随访各阶段病变的活性。PET-CT结合了CT的解剖细节和（18）F-氟代脱氧葡萄糖（FDG）成像的生理活性。我们得出结论，PET-CT信息在评估疾病活性和治疗反应方面具有临床实用性，并且能提供从锝99m亚甲基二膦酸盐骨扫描或X线片无法获得的信息。
