18F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描在儿科肿瘤学中的应用：已确立的和新出现的应用
F-FDG PET-CT in paediatric oncology: established and emerging applications.
作者信息
Chambers Greg, Frood Russell, Patel Chirag, Scarsbrook Andrew
机构信息
1 Department of Nuclear Medicine, Leeds Teaching Hospitals NHS Trust , Leeds , UK.
2 Radiotherapy Research Group, Leeds Institute of Cancer and Pathology, University of Leeds , Leeds , UK.
出版信息
Br J Radiol. 2019 Feb;92(1094):20180584. doi: 10.1259/bjr.20180584. Epub 2018 Nov 28.
Abstract
Accurate staging and response assessment is vital in the management of childhood malignancies. Fluorine-18 fluorodeoxyglucose positron emission tomography/CT (FDG PET-CT) provides complimentary anatomical and functional information. Oncological applications of FDG PET-CT are not as well-established within the paediatric population compared to adults. This article will comprehensively review established oncological PET-CT applications in paediatric oncology and provide an overview of emerging and future developments in this domain.
摘要
准确的分期和疗效评估对于儿童恶性肿瘤的治疗至关重要。氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET-CT）可提供补充性的解剖学和功能信息。与成人相比，FDG PET-CT在儿科人群中的肿瘤学应用尚未得到充分确立。本文将全面回顾FDG PET-CT在儿科肿瘤学中已确立的肿瘤学应用，并概述该领域的新兴和未来发展情况。
相似文献
1
F-FDG PET-CT in paediatric oncology: established and emerging applications.18F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描在儿科肿瘤学中的应用：已确立的和新出现的应用
Br J Radiol. 2019 Feb;92(1094):20180584. doi: 10.1259/bjr.20180584. Epub 2018 Nov 28.
2
FDG PET/CT in oncology: "raising the bar".FDG PET/CT 在肿瘤学中的应用：“提高标准”。
Clin Radiol. 2010 Jul;65(7):522-35. doi: 10.1016/j.crad.2010.01.003. Epub 2010 Mar 4.
3
[PET Research in Clinical Oncology].[临床肿瘤学中的正电子发射断层显像研究]
Igaku Butsuri. 2022;42(2):80-87. doi: 10.11323/jjmp.42.2_80.
4
FDG PET Hybrid Imaging.氟代脱氧葡萄糖正电子发射断层显像融合成像
Recent Results Cancer Res. 2020;216:625-667. doi: 10.1007/978-3-030-42618-7_19.
5
The impact of F-FDG PET on initial staging and therapy planning of pediatric soft-tissue sarcoma patients.氟代脱氧葡萄糖正电子发射断层扫描对儿科软组织肉瘤患者初始分期和治疗计划的影响。
Pediatr Radiol. 2020 Feb;50(2):252-260. doi: 10.1007/s00247-019-04530-1. Epub 2019 Oct 18.
6
Comparison of FDG PET/MRI and FDG PET/CT in Pediatric Oncology in Terms of Anatomic Correlation of FDG-positive Lesions.18F-氟代脱氧葡萄糖正电子发射断层显像/磁共振成像（FDG PET/MRI）与18F-氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描（FDG PET/CT）在儿童肿瘤学中关于FDG阳性病变解剖相关性的比较
J Pediatr Hematol Oncol. 2019 Oct;41(7):542-550. doi: 10.1097/MPH.0000000000001465.
7
Fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) computed tomography (CT) for the detection of bone, lung, and lymph node metastases in rhabdomyosarcoma.氟-18-氟代脱氧葡萄糖（FDG）正电子发射断层扫描（PET）计算机断层扫描（CT）用于检测横纹肌肉瘤中的骨、肺和淋巴结转移。
Cochrane Database Syst Rev. 2021 Nov 9;11(11):CD012325. doi: 10.1002/14651858.CD012325.pub2.
8
DaPeCa-7: comparative assessment of fluorodeoxyglucose positron emission tomography/computed tomography (CT) and conventional diagnostic CT in diagnosis of lymph node metastases, distant metastases and incidental findings in patients with invasive penile cancer.DaPeCa-7：氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（CT）与常规诊断 CT 对比评估在浸润性阴茎癌患者淋巴结转移、远处转移和偶然发现中的诊断价值。
BJU Int. 2021 Feb;127(2):254-262. doi: 10.1111/bju.15206. Epub 2020 Sep 7.
9
The role of F-FDG PET CT in common gynaecological malignancies.F-FDG PET CT在常见妇科恶性肿瘤中的作用。
Br J Radiol. 2017 Nov;90(1079):20170283. doi: 10.1259/bjr.20170283. Epub 2017 Aug 22.
10
Staging canine patients with appendicular osteosarcoma utilizing fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography compared to whole body computed tomography.利用氟-18 氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描对附肢骨肉瘤犬患者进行分期，与全身计算机断层扫描相比。
Vet Comp Oncol. 2022 Sep;20(3):541-550. doi: 10.1111/vco.12805. Epub 2022 Mar 11.
引用本文的文献
1
Value of 18F-FDG PET/CT Scans in Staging and Follow-Up of Pediatric Langerhans Cell Histiocytosis: Comparison to CT and/or MRI.18F-FDG PET/CT扫描在儿童朗格汉斯细胞组织细胞增多症分期及随访中的价值：与CT和/或MRI的比较
Children (Basel). 2025 Aug 20;12(8):1089. doi: 10.3390/children12081089.
2
Assessment of reduced F-FDG dosage in pediatric PET/MR imaging through randomized down-sampling.通过随机下采样评估儿科PET/MR成像中降低的F-FDG剂量
Ann Nucl Med. 2025 Jun 17. doi: 10.1007/s12149-025-02066-z.
3
Hepatoblastoma.肝母细胞瘤
Nat Rev Dis Primers. 2025 May 22;11(1):36. doi: 10.1038/s41572-025-00620-7.
4
A bibliometric analysis based on hotspots and frontier trends of positron emission tomography/computed tomography utility in bone and soft tissue sarcoma.基于正电子发射断层扫描/计算机断层扫描在骨与软组织肉瘤应用中的热点和前沿趋势的文献计量分析
Front Oncol. 2024 Jun 21;14:1344643. doi: 10.3389/fonc.2024.1344643. eCollection 2024.
5
Outcome and prognostic factors of pediatric patients with Hodgkin lymphoma: a single-center experience.儿童霍奇金淋巴瘤患者的预后和影响因素：单中心经验。
J Egypt Natl Canc Inst. 2023 Sep 11;35(1):29. doi: 10.1186/s43046-023-00189-w.
6
Anthracycline cardiotoxicity: current methods of diagnosis and possible role of F-FDG PET/CT as a new biomarker.蒽环类药物心脏毒性：当前的诊断方法以及F-FDG PET/CT作为一种新生物标志物的潜在作用。
Cardiooncology. 2023 Mar 27;9(1):17. doi: 10.1186/s40959-023-00161-6.
7
Clinical value of F-FDG PET/CT in the management of HIV-associated lymphoma.F-FDG PET/CT在HIV相关淋巴瘤管理中的临床价值。
Front Oncol. 2023 Jan 26;13:1117064. doi: 10.3389/fonc.2023.1117064. eCollection 2023.
8
Imaging of pediatric bone tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper.儿童骨肿瘤的影像学：COG 诊断成像委员会/SPR 肿瘤学委员会白皮书。
Pediatr Blood Cancer. 2023 Jun;70 Suppl 4(Suppl 4):e30000. doi: 10.1002/pbc.30000. Epub 2022 Oct 17.
9
Handheld PET Probe for Pediatric Cancer Surgery.用于儿科癌症手术的手持式PET探头。
Cancers (Basel). 2022 Apr 29;14(9):2221. doi: 10.3390/cancers14092221.
10
Clinical Perspectives for F-FDG PET Imaging in Pediatric Oncology: Μetabolic Tumor Volume and Radiomics.小儿肿瘤学中F-FDG PET成像的临床前景：代谢肿瘤体积与放射组学
Metabolites. 2022 Feb 28;12(3):217. doi: 10.3390/metabo12030217.
本文引用的文献
1
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).2017年PRETEXT：针对儿童原发性肝脏恶性肿瘤的放射学分期系统，为儿科肝脏国际肿瘤试验（PHITT）进行了修订。
Pediatr Radiol. 2018 Apr;48(4):536-554. doi: 10.1007/s00247-018-4078-z. Epub 2018 Feb 9.
2
Importance of whole-body imaging with complete coverage of hands and feet in alveolar rhabdomyosarcoma staging.在肺泡横纹肌肉瘤分期中对手足进行全面覆盖的全身成像的重要性。
Pediatr Radiol. 2018 May;48(5):648-657. doi: 10.1007/s00247-017-4066-8. Epub 2018 Jan 24.
3
Comparison of diagnosing and staging accuracy of PET (CT) and MIBG on patients with neuroblastoma: Systemic review and meta-analysis.PET（CT）与MIBG对神经母细胞瘤患者的诊断及分期准确性比较：系统评价与荟萃分析
J Huazhong Univ Sci Technolog Med Sci. 2017 Oct;37(5):649-660. doi: 10.1007/s11596-017-1785-x. Epub 2017 Oct 20.
4
F-FDG PET/CT as an Indicator of Survival in Ewing Sarcoma of Bone.F-FDG PET/CT作为骨尤文肉瘤生存的指标
J Cancer. 2017 Aug 25;8(15):2892-2898. doi: 10.7150/jca.20077. eCollection 2017.
5
Early assessment of response to induction therapy in acute myeloid leukemia using F-FLT PET/CT.利用F-FLT PET/CT对急性髓系白血病诱导治疗反应进行早期评估。
EJNMMI Res. 2017 Sep 16;7(1):75. doi: 10.1186/s13550-017-0326-8.
6
Consensus and controversies regarding the treatment of rhabdomyosarcoma.关于横纹肌肉瘤治疗的共识与争议
Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26809. Epub 2017 Sep 14.
7
FDG PET/CT appearance of local osteosarcoma recurrences in pediatric patients.儿童患者局部骨肉瘤复发的氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描表现
Pediatr Radiol. 2017 Dec;47(13):1800-1808. doi: 10.1007/s00247-017-3963-1. Epub 2017 Sep 8.
8
Prognostic value of FDG-PET indices for the assessment of histological response to neoadjuvant chemotherapy and outcome in pediatric patients with Ewing sarcoma and osteosarcoma.FDG-PET指数对评估尤文肉瘤和骨肉瘤患儿新辅助化疗的组织学反应及预后的预后价值。
PLoS One. 2017 Aug 25;12(8):e0183841. doi: 10.1371/journal.pone.0183841. eCollection 2017.
9
Monitoring of plexiform neurofibroma in children and adolescents with neurofibromatosis type 1 by [ F]FDG-PET imaging. Is it of value in asymptomatic patients?利用[F]FDG-PET成像监测1型神经纤维瘤病儿童和青少年的丛状神经纤维瘤。对无症状患者有价值吗？
Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26733. Epub 2017 Aug 3.
10
Prediction of outcome in pediatric Hodgkin lymphoma based on interpretation of FDG-PET/CT according to ΔSUV, Deauville 5-point scale and IHP criteria.基于根据SUV变化、Deauville 5分法和IHP标准对FDG-PET/CT进行解读的儿童霍奇金淋巴瘤预后预测
Ann Nucl Med. 2017 Nov;31(9):660-668. doi: 10.1007/s12149-017-1196-x. Epub 2017 Jul 24.
Zotero 插件