Yamada Hideyasu, Ishii Wataru, Ito Satoshi, Iwanami Keiichi, Ogishima Hiroshi, Suzuki Takeshi, Mamura Mizuko, Goto Daisuke, Matsumoto Isao, Tsutsumi Akito, Sumida Takayuki
Clinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Mod Rheumatol. 2007;17(3):243-6. doi: 10.1007/s10165-007-0573-z. Epub 2007 Jun 20.
A 54-year-old woman complaining of muscle weakness and weight loss was admitted to our hospital with suspected polymyositis. Muscle biopsy revealed Langhans-type giant cells and noncaseating granulomas. Therefore, sarcoid myositis was diagnosed. The patient was treated with prednisolone, and the symptoms improved gradually. Generally, sarcoidosis is identified clinically in patients with foggy vision or mediastinal lymphadenopathy, but muscular weakness may be an infrequently observed initial symptom. Sarcoidosis should be considered in the differential diagnosis of polymyositis.
一名54岁女性因肌肉无力和体重减轻入院，怀疑患有多发性肌炎。肌肉活检发现朗汉斯型巨细胞和非干酪样肉芽肿。因此，诊断为结节病性肌炎。患者接受泼尼松龙治疗，症状逐渐改善。一般来说，结节病在视力模糊或纵隔淋巴结肿大的患者中通过临床诊断，但肌肉无力可能是一种较少见的初始症状。在多发性肌炎的鉴别诊断中应考虑结节病。
