Moore Timothy J, Ritter Alison, Caulkins Jonathan P
Turning Point Alcohol and Drug Centre. Fitzroy, VIC, Australia.
Drug Alcohol Rev. 2007 Jul;26(4):369-78. doi: 10.1080/09595230701373883.
This study compares the costs and consequences of three interventions for reducing heroin dependency: pharmacotherapy maintenance, residential rehabilitation and prison.
Using Australian data, the interventions' cost - consequence ratio was estimated, taking into consideration reduction in heroin use during the intervention; the length of intervention; and post-intervention effects (as measured by abstinence rates). Sensitivity analyses were conducted, including varying the magnitude and duration of treatment effects, and ascribing positive outcomes only to treatment completers. A hybrid model that combined pharmacotherapy maintenance with a prison term was also considered.
If the post-programme abstinence rates are sustained for 2 years, then for an average heroin user the cost of averting a year of heroin use is approximately AUD$5000 for pharmacotherapy maintenance, AUD$11,000 for residential rehabilitation and AUD$52 000 for prison. Varying the parameters does not change the ranking of the programmes. If the completion rate in pharmacotherapy maintenance was raised above 95% (by the threat of prison for non-completers), the combined model of treatment plus prison may become the most cost-effective option.
Relative performance in terms of costs and consequences is an important consideration in the policy decision-making process, and quantitative data such as those reported herein can provide insights pertinent to evidence-based policy.
本研究比较了三种减少海洛因依赖干预措施的成本与效果:药物维持治疗、住院康复治疗和监禁。
利用澳大利亚的数据,估计了干预措施的成本 - 效果比,同时考虑了干预期间海洛因使用量的减少、干预时长以及干预后的效果(以戒断率衡量)。进行了敏感性分析,包括改变治疗效果的大小和持续时间,以及仅将积极结果归因于治疗完成者。还考虑了一种将药物维持治疗与监禁期相结合的混合模式。
如果项目后的戒断率持续两年,那么对于一名普通海洛因使用者,药物维持治疗避免一年海洛因使用的成本约为5000澳元,住院康复治疗为11000澳元,监禁为52000澳元。改变参数不会改变这些项目的排名。如果药物维持治疗的完成率提高到95%以上(通过对未完成者监禁的威胁),治疗加监禁的混合模式可能成为最具成本效益的选择。
在政策决策过程中,成本和效果方面的相对表现是一个重要考虑因素,本文所报告的此类定量数据可为基于证据的政策提供相关见解。