Seybold U, Talati N J, Kizilbash Q, Shah M, Blumberg H M, Franco-Paredes C
Division of Infectious Diseases, Medicall Policlinic, Ludwig Maximilian University Munich, Germany.
Infection. 2007 Jun;35(3):190-3. doi: 10.1007/s15010-007-6058-3.
Community Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) is an emerging pathogen with increasing clinical significance. Initially recognized as a cause of skin and soft tissue infections, it has soon been shown to cause life threatening illnesses. We describe two cases of osteomyelitis of the femur in young otherwise healthy adults. Initially a preliminary diagnosis of osteosarcoma was suggested by radiologic studies and both patients underwent an excisional biopsy. Following identification of the pathogen as CA-MRSA (Panton-Valentine leukocidin positive USA300 clone), both patients were successfully treated with prolonged courses of vancomycin.
社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）是一种新兴病原体，其临床意义日益增加。最初被认为是皮肤和软组织感染的病因，很快就被证明可导致危及生命的疾病。我们描述了两例股骨骨髓炎病例，患者均为年轻且原本健康的成年人。最初，放射学检查提示初步诊断为骨肉瘤，两名患者均接受了切除活检。在病原体被鉴定为CA-MRSA（Panton-Valentine杀白细胞素阳性的USA300克隆）后，两名患者均通过长期使用万古霉素成功治愈。
