Hong De-fei, Zheng Xue-yong, Peng Shu-you, Gao Min, Wu Jia-guo, Cao Qian
Department of General Surgery, Sir Run Run Shaw Hospital, Medical college of Zhejiang University, Hangzhou 310016, China.
Zhonghua Yi Xue Za Zhi. 2007 Mar 27;87(12):820-2.
To evaluate the safety and efficacy of laparoscopic splenectomy (LS) and pericardial devascularization in treatment of portal hypertension due to liver cirrhosis.
Twenty three cases with hepatitis B and schistosoma cirrhosis and portal hypertension underwent LS and paraesophagogastric devascularization performed by one treatment team. Follow-up was conducted for 9 months.
LS combined with pericardial devascularization was successfully performed on these 20 cases. Three cases were converted to open surgery due to intra-operative bleeding. The mean operative time was 235 min (180 - 350), and mean intra-operative blood loss was 520 ml (200 - 1600 ml). All patients were treated with plasma transfusion, antibiotics, and abdominal drainage post-operatively. Peristalsis of stomach and intestine recovered 24 - 72 hours after operation. The mean hospitalization time was 8.5 days (6 - 17 days). The peri-operative complication included plural effusion in 3 cases and subphrenic abscess in one case, .mild ascites in two cases, and wound dehiscence in one case. No mortality occurred. Rebleeding rare was 0%.
LS combined with pericardial devascularization is relatively safe and effective in treatment of portal hypertension due to liver cirrhosis. The keys to success include experienced laparoscopic skills, use of harmonic scalpel and careful manipulation.
评估腹腔镜脾切除术(LS)联合贲门周围血管离断术治疗肝硬化门静脉高压症的安全性和疗效。
23例乙型肝炎和血吸虫性肝硬化合并门静脉高压症患者由同一治疗团队实施LS及贲门周围血管离断术,随访9个月。
20例成功实施LS联合贲门周围血管离断术,3例因术中出血中转开腹手术。平均手术时间235分钟(180 - 350分钟),平均术中出血量520毫升(200 - 1600毫升)。术后所有患者均给予输血、抗生素及腹腔引流治疗。胃肠蠕动于术后24 - 72小时恢复。平均住院时间8.5天(6 - 17天)。围手术期并发症包括胸腔积液3例、膈下脓肿1例、轻度腹水2例、伤口裂开1例。无死亡病例。再出血率为0%。
LS联合贲门周围血管离断术治疗肝硬化门静脉高压症相对安全有效。成功的关键包括熟练的腹腔镜技术、使用超声刀及仔细操作。