Webb Aimee L, Villamor Eduardo
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, MA, 02115, USA.
Nutr Rev. 2007 May;65(5):181-217. doi: 10.1111/j.1753-4887.2007.tb00298.x.
The purpose of this manuscript is to review the impact of supplementation with vitamins E and C, carotenoids, and the B vitamins on parameters of innate and adaptive immune function as reported from clinical trials in humans. There is evidence to support causal effects of supplementation with vitamins E and C and the carotenoids singly and in combination on selected aspects of immunity, including the functional capacity of innate immune cells, lymphocyte proliferation, and the delayed-type hypersensitivity (DTH) response. Controlled intervention trials of B vitamin-containing multivitamin supplements suggest beneficial effects on immune parameters and clinical outcomes in HIV-positive individuals.
本手稿的目的是回顾维生素E、维生素C、类胡萝卜素和B族维生素补充剂对人类临床试验中所报告的先天性和适应性免疫功能参数的影响。有证据支持单独或联合补充维生素E、维生素C和类胡萝卜素对免疫特定方面的因果效应，包括先天性免疫细胞的功能能力、淋巴细胞增殖和迟发型超敏反应（DTH）。含B族维生素的多种维生素补充剂的对照干预试验表明，对HIV阳性个体的免疫参数和临床结果有有益影响。
