Nakahira Atsushi, Ogino Hitoshi, Sasaki Hiroaki, Katakami Nobuyuki
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.
Eur J Cardiothorac Surg. 2007 Aug;32(2):388-90. doi: 10.1016/j.ejcts.2007.04.019. Epub 2007 Jun 13.
Malignant pulmonary artery tumors represented by sarcomas are rare, but fatal. Early diagnosis and radical surgical resection offer the only chance for survival. However, surgical intervention has some challenging aspects, and prognosis is poor even after tumor resection. We report a case of a pulmonary artery sarcoma between the right ventricular outflow tract and the pulmonary artery branches. The tumor was aggressively extracted with reconstruction using a cryopreserved pulmonary valved allograft, followed by adjuvant chemoradiotherapy. At 56 months after surgery, the patient is well without any evidence of recurrence, demonstrating that aggressive surgical resection with adjuvant chemoradiotherapy can prolong survival.
以肉瘤为代表的恶性肺动脉肿瘤较为罕见，但预后凶险。早期诊断并进行根治性手术切除是生存的唯一机会。然而，手术干预存在一些挑战性，即便肿瘤切除后预后仍较差。我们报告一例发生于右心室流出道与肺动脉分支之间的肺动脉肉瘤病例。该肿瘤通过使用冷冻保存的带瓣肺动脉同种异体移植物进行重建后被积极切除，随后接受辅助放化疗。术后56个月，患者情况良好，无任何复发迹象，表明积极的手术切除联合辅助放化疗可延长生存期。
