Fu K K, Ray J W, Chan E K, Phillips T L
AJR Am J Roentgenol. 1976 Jan;126(1):107-15. doi: 10.2214/ajr.126.1.107.
In 204 patients with squamous cell carcinoma of the oral tongue treated with radiation therapy, the most significant prognostic factors appeared to be the presence of neck lymph node metastasis on presentation and the status of the disease three months after treatment. The most common site of failure was the primary lesion, either alone or with neck disease. External irradiation alone was seldom successful. Use of peroral cone irradiation or interstitial implants, either alone or in combination with external irradiation, achieved good local control in early lesions. When the primary tumor was uncontrolled by radiation therapy, salvage with surgery was rare. When failure occurred in the neck alone, radical neck dissection was successful in the majority of cases.
在204例接受放射治疗的口腔舌鳞状细胞癌患者中,最重要的预后因素似乎是就诊时存在颈部淋巴结转移以及治疗后三个月的疾病状况。最常见的复发部位是原发灶,可为单独原发灶或合并颈部疾病。单纯外照射很少成功。单独使用经口锥形照射或组织间植入,或与外照射联合使用,在早期病变中可实现良好的局部控制。当原发肿瘤无法通过放射治疗控制时,很少能通过手术挽救。当仅在颈部出现复发时,大多数病例行根治性颈清扫术是成功的。