Rashid R M, Khachemoune A
Department of Dermatology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
J Eur Acad Dermatol Venereol. 2007 Jul;21(6):725-31. doi: 10.1111/j.1468-3083.2007.02250.x.
Trigeminal trophic syndrome (TTS) is a rare cause of facial ulceration, which is believed to develop after insult to the trigeminal ganglia or other parts of the peripheral/central nervous system in the trigeminal pathway. The pathogenesis of TTS is poorly understood. Developing a better understanding of TTS will allow early recognition and improved treatment. Although the ulcers develop predominantly on the ala nasi, the literature on ulcer locations is limited. In this article, we review the epidemiologic aspects of TTS, expand on our knowledge of the anatomic location of the ulcers, and discuss current theories for its aetiology and briefly review the approaches to its management.
三叉神经营养综合征（TTS）是面部溃疡的一种罕见病因，据信是在三叉神经节或三叉神经通路的外周/中枢神经系统其他部位受到损伤后发生的。TTS的发病机制尚不清楚。更好地了解TTS将有助于早期识别和改善治疗。尽管溃疡主要发生在鼻翼，但关于溃疡位置的文献有限。在本文中，我们回顾了TTS的流行病学方面，扩展了我们对溃疡解剖位置的认识，并讨论了其病因的当前理论，并简要回顾了其治疗方法。
