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缺血性中风后三叉神经营养综合征伴神经痛——病例报告

Trigeminal trophic syndrome associated with neuralgia after ischemic stroke-a case report.

作者信息

Rybak-D Obyrn Joanna, Alicja Lewandowska Julia, Joanna Machoń Natalia, Agnieszka Owczarczyk-Saczonek, Waldemar Placek

机构信息

Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology University of Warmia and Mazury Olsztyn Poland.

Medical Faculty University of Warmia and Mazury Olsztyn Poland.

出版信息

Clin Case Rep. 2023 Aug 7;11(8):e7711. doi: 10.1002/ccr3.7711. eCollection 2023 Aug.

DOI:10.1002/ccr3.7711
PMID:37554578
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10405243/
Abstract

Trigeminal trophic syndrome (TTS) is a rare condition resulting from self-manipulation of the skin after an injury to the trigeminal nerve. We describe the case of a 70-year-old woman who was hospitalized because of erythema, ulceration, and crusts on the right side of her face, accompanied by itching, burning, and irritation forcing self-manipulation of the skin. She had been previously repeatedly treated with antibiotics, acyclovir, and topical medications without any improvement. Her medical history revealed an episode of ischemic stroke in 2016, after which a deformation and partial atrophy of the right ala nasi appeared. Trigeminal neuropathy was confirmed by a neurological consultation. Diagnosis and treatment of TTS requires a multidisciplinary approach. Awareness of this disease should be raised to enable proper diagnosis and management of difficult-to-treat facial ulcers that cannot be explained by common causes.

摘要

三叉神经营养综合征(TTS)是一种罕见的疾病,由三叉神经损伤后自我搔抓皮肤所致。我们报告一例70岁女性病例,该患者因右侧面部红斑、溃疡和结痂入院,伴有瘙痒、烧灼感和刺激感,导致其自我搔抓皮肤。她此前曾多次接受抗生素、阿昔洛韦和局部用药治疗,但均无改善。她的病史显示2016年曾发生缺血性中风,之后右侧鼻翼出现变形和部分萎缩。经神经科会诊确诊为三叉神经病变。TTS的诊断和治疗需要多学科方法。应提高对这种疾病的认识,以便对常见病因无法解释的难治性面部溃疡进行正确诊断和管理。

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本文引用的文献

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Trigeminal trophic syndrome: an updated review.三叉神经营养综合征:更新的综述。
Int J Dermatol. 2019 May;58(5):530-537. doi: 10.1111/ijd.14098. Epub 2018 Jun 21.
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Trigeminal trophic syndrome following anterior inferior cerebellar artery infarction.小脑下前动脉梗死继发三叉神经营养综合征。
BMJ Case Rep. 2018 Apr 20;2018:bcr-2018-225278. doi: 10.1136/bcr-2018-225278.
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Atypical Trigeminal Trophic Syndrome: An Unusual Cause of Facial Ulceration.非典型三叉神经营养综合征:面部溃疡的罕见病因。
Acta Derm Venereol. 2017 Aug 31;97(8):971-972. doi: 10.2340/00015555-2675.
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Cicatricial Eyelid Paralysis Secondary to Trigeminal Trophic Syndrome.继发于三叉神经营养综合征的瘢痕性眼睑麻痹
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Carbamazepine as the only effective treatment in a 52-year-old man with trigeminal trophic syndrome.卡马西平是一名52岁三叉神经营养综合征男性患者的唯一有效治疗药物。
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Herpes zoster-associated trigeminal trophic syndrome: a case report and review.带状疱疹相关性三叉神经营养综合征:一例报告及文献复习
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Herpetic trigeminal trophic syndrome in an infant.婴儿疱疹性三叉神经营养综合征
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