Jackson A, Burton I E
Department of Diagnostic Radiology, University of South Manchester, U.K.
Eur J Radiol. 1991 Nov-Dec;13(3):203-6. doi: 10.1016/0720-048x(91)90030-y.
A patient with classical POEMS syndrome associated with a myeloproliferative disorder is presented, in whom extensive arterial calcification was seen at an early age in the absence of other predisposing factors. Radiographs also demonstrated several small discrete sclerotic foci elsewhere in the skeleton and areas of new bone formation around the spine which were described in previous cases. Histological studies in this patient demonstrated an osteosclerotic solitary plasmacytoma of bone and Castleman's disease of lymph nodes, both of which have previously been causally associated with POEMS syndrome. In addition, dermal infiltration by mast cells was demonstrated.
本文报告了一名患有与骨髓增殖性疾病相关的经典POEMS综合征患者，该患者在无其他易感因素的情况下，早年即出现广泛的动脉钙化。X线片还显示骨骼其他部位有几个小的离散性硬化灶以及脊柱周围有新骨形成区域，这些情况在既往病例中已有描述。该患者的组织学研究显示为骨硬化性孤立性骨浆细胞瘤和淋巴结Castleman病，这两种疾病此前均被认为与POEMS综合征存在因果关系。此外，还证实有肥大细胞浸润皮肤。
