Brown Richard A, Abrantes Ana M, Strong David R, Mancebo Maria C, Menard Julie, Rasmussen Steven A, Greenberg Benjamin D
Butler Hospital/Brown Medical School, Providence, RI 02906, USA.
J Nerv Ment Dis. 2007 Jun;195(6):514-20. doi: 10.1097/01.nmd.0000253730.31610.6c.
This preliminary study examined the impact of aerobic exercise as an adjunctive intervention to regular care in reducing obsessive compulsive disorder (OCD) symptoms in a clinical sample. Fifteen patients (53% male; mean age = 44.4 years) receiving behavioral therapy and/or pharmacotherapy for OCD and who still demonstrated clinically significant OCD symptoms (i.e., Yale-Brown obsessive compulsive scale, Y-BOCS scores above 16) were enrolled in a 12-week moderate-intensity exercise intervention. Measures of OCD symptom severity were obtained at baseline, end of treatment, and at 3- and 6-week, and 6-month follow-up. Study findings at the end of this 12-week aerobic exercise intervention point to a beneficial effect (Cohen's d = 1.69) on reduction in OCD symptom severity. Further, reductions in OCD symptom severity appear to persist 6 months later. Lastly, improvement in overall sense of well-being was observed after the 12-week intervention. Results of this study suggest that a randomized clinical trial evaluating the efficacy of this 12-week aerobic exercise intervention is warranted.
这项初步研究考察了有氧运动作为常规护理辅助干预措施，对临床样本中强迫症（OCD）症状减轻的影响。15名接受强迫症行为疗法和/或药物治疗但仍表现出临床上显著强迫症症状（即耶鲁-布朗强迫症量表，Y-BOCS评分高于16）的患者（53%为男性；平均年龄 = 44.4岁）参加了为期12周的中等强度运动干预。在基线、治疗结束时、3周、6周和6个月随访时获取强迫症症状严重程度的测量数据。这项为期12周的有氧运动干预结束时的研究结果表明，对减轻强迫症症状严重程度有有益效果（科恩d值 = 1.69）。此外，强迫症症状严重程度的减轻似乎在6个月后仍持续存在。最后，在为期12周的干预后观察到总体幸福感有所改善。本研究结果表明，有必要进行一项随机临床试验来评估这种为期12周的有氧运动干预的疗效。
