辐射对胃肠动力的影响。
Effects of radiation upon gastrointestinal motility.
作者信息
Otterson Mary F
机构信息
Department of Surgery, Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
出版信息
World J Gastroenterol. 2007 May 21;13(19):2684-92. doi: 10.3748/wjg.v13.i19.2684.
Abstract
Whether due to therapeutic or belligerent exposure, the gastrointestinal effects of irradiation produce symptoms dreaded by a majority of the population. Nausea, vomiting, diarrhea and abdominal cramping are hallmarks of the prodromal phase of radiation sickness, occurring hours to days following radiation exposure. The prodromal phase is distinct from acute radiation sickness in that the absorptive, secretory and anatomic changes associated with radiation damage are not easily identifiable. It is during this phase of radiation sickness that gastrointestinal motility significantly changes. In addition, there is evidence that motor activity of the gut contributes to some of the acute and chronic effects of radiation.
摘要
无论是由于治疗性照射还是战时照射，辐射对胃肠道的影响都会产生让大多数人惧怕的症状。恶心、呕吐、腹泻和腹部绞痛是辐射病前驱期的特征，在辐射暴露后数小时至数天内出现。前驱期与急性辐射病不同，因为与辐射损伤相关的吸收、分泌和解剖学变化不易识别。正是在辐射病的这个阶段，胃肠蠕动发生了显著变化。此外，有证据表明肠道的运动活动会导致辐射的一些急性和慢性影响。
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